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However, little is known about how psychiatric comorbidity manifests among people with PTSD, particularly with regard to concurrent diagnoses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Latent class analysis (LCA) was used to characterize discrete classes of PTSD comorbidity using past year DSM\u20105 diagnostic standards among a large nationally representative epidemiologic sample of U.S. adults. Follow\u2010up analyses compared participant characteristics across latent classes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The LCA was best characterized by five classes: low comorbidity, distress\u2010fear, distress\u2010externalizing, mania\u2010fear\u2010externalizing, and mania\u2010externalizing. 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