{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T21:59:36Z","timestamp":1788991176344,"version":"build-2803163510"},"reference-count":76,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T00:00:00Z","timestamp":1749513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Clin Psychol"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cognitive impairment in manic patients involves neurocognitive and theory of mind (ToM) impairments. This study aims to investigate cognitive impairment among manic patients and their first\u2010degree relatives (FDRs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 31 manic inpatients, 31 unaffected relatives, and 30 healthy controls (HCs) were investigated using the Reading the Mind in Eye Test (RMET) and Hinting Task (HT). The intelligence quotient (IQ), attention, working memory, executive functions, fluency and processing speed were also assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients and their relatives scored lower than controls on Theory of Mind reasoning and several neurocognitive measures. Regression analysis of the total sample indicated that a mania diagnosis or a FDR was strongly related to lower ToM reasoning performance. The deficits in ToM among patients were related to years of education.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Due to the comparable performance of ToM between patients and their relatives, the reasoning aspect of ToM may represent a trait marker for bipolar disorder (BD). The deficits in ToM in patients with BD are partly independent of neurocognition.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jclp.70003","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T13:59:43Z","timestamp":1749563983000},"page":"868-877","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Theory of Mind and Neurocognition in Bipolar Mania Patients and Their Unaffected First\u2010Degree Relatives"],"prefix":"10.1002","volume":"81","author":[{"given":"Jing","family":"Zeng","sequence":"first","affiliation":[{"name":"Shenzhen Mental Health Center Shenzhen Kangning Hospital Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tie\u2010bang","family":"Liu","sequence":"additional","affiliation":[{"name":"Shenzhen Mental Health Center Shenzhen Kangning Hospital Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5354-3666","authenticated-orcid":false,"given":"Yang\u2010hui","family":"Liu","sequence":"additional","affiliation":[{"name":"Shenzhen Mental Health Center Shenzhen Kangning Hospital Shenzhen China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/NMD.0000000000001408"},{"key":"e_1_2_11_3_1","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association. ed.2013.Diagnostic and Statistical Manual of Mental Disorders: DSM\u20105(5th ed). American Psychiatric Association.","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291707001675"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-7610.00715"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpsy.2017.06.003"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291715001993"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2005.11.003"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2017.02.009"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2005.00570.x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2016.06.007"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2008.12.020"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2013.00661"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11126-019-09627-2"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2012.05.009"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2016.08.002"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0920-9964(95)00024-G"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2019.01.015"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2012.01011.x"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291703001570"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2017.09.039"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0246908"},{"key":"e_1_2_11_23_1","unstructured":"Eyes Test (Adult). n.d. Autism Research Centre.https:\/\/www.autismresearchcentre.com\/tests\/eyes-test-adult\/."},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2013.4100"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1192\/j.eurpsy.2020.66"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2009.184"},{"key":"e_1_2_11_27_1","unstructured":"Gong Y.1992.Wechsler Adult Intelligence Scale\u2010Revised in China Version. Hunan Medical College."},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291719002794"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.4.636"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20624"},{"key":"e_1_2_11_31_1","doi-asserted-by":"crossref","unstructured":"Guglielmo R.(2021).Evaluating Endophenotypes for Bipolar Disorder.","DOI":"10.1186\/s40345-021-00220-w"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044-8341.1959.tb00467.x"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2044-8260.1967.tb00530.x"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2016.03.043"},{"issue":"12","key":"e_1_2_11_35_1","first-page":"1046","article-title":"Age \u00b7 Related Differences in Hku \u00b7 Ahmu Neuropsychological Assessment Among Healthy Crowds","volume":"21","author":"Hu P.","year":"2021","journal-title":"Chinese Journal of Contemporary Neurology and Neurosurgery"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.paid.2012.11.022"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadr.2023.100595"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00008-3"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1080\/13546805.2020.1829579"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0016277"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2007.08.009"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjc.12318"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2004.10.001"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1080\/00207594.2012.673724"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.13303"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.330"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.161.2.262"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2011.04.033"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31544-0"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2009.08.017"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2021.152258"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-021-01265-9"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2020.11.011"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2005.00254.x"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2018.03.013"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40345-024-00340-z"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2014.05.041"},{"key":"e_1_2_11_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2018.07.045"},{"key":"e_1_2_11_59_1","doi-asserted-by":"publisher","DOI":"10.1080\/02699930601117096"},{"key":"e_1_2_11_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2014.07.038"},{"key":"e_1_2_11_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandc.2003.04.002"},{"key":"e_1_2_11_62_1","doi-asserted-by":"publisher","DOI":"10.1162\/089892904322926755"},{"key":"e_1_2_11_63_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291721004517"},{"key":"e_1_2_11_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/NMD.0000000000000595"},{"key":"e_1_2_11_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.12.094"},{"key":"e_1_2_11_66_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291707002541"},{"key":"e_1_2_11_67_1","doi-asserted-by":"publisher","DOI":"10.1176\/jnp.2009.21.1.59"},{"key":"e_1_2_11_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn844"},{"key":"e_1_2_11_69_1","doi-asserted-by":"publisher","DOI":"10.1177\/0004867420924109"},{"key":"e_1_2_11_70_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.107.035899"},{"key":"e_1_2_11_71_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.XME.0000508434.65320.b4"},{"key":"e_1_2_11_72_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.186.1.32"},{"key":"e_1_2_11_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2007.01055.x"},{"key":"e_1_2_11_74_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-015-0657-2"},{"key":"e_1_2_11_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2015.10.026"},{"key":"e_1_2_11_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2010.00854.x"},{"key":"e_1_2_11_77_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.133.5.429"}],"container-title":["Journal of Clinical Psychology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jclp.70003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T18:11:17Z","timestamp":1756750277000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jclp.70003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,10]]},"references-count":76,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1002\/jclp.70003"],"URL":"https:\/\/doi.org\/10.1002\/jclp.70003","archive":["Portico"],"relation":{},"ISSN":["0021-9762","1097-4679"],"issn-type":[{"value":"0021-9762","type":"print"},{"value":"1097-4679","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,10]]},"assertion":[{"value":"2024-05-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}