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There is emerging evidence on the link between stress and hot flashes, yet findings have been limited and mixed. Most studies have relied primarily on between\u2010person relationships and have overlooked important nuances of whether stress on any given day is associated with more severe hot flashes on that same day. Our study bridges this gap by examining both the between\u2010 and within\u2010person relationships between daily psychological stress (number of stressors, stressor severity sum, and stressor severity average) and hot flash severity among women who reported experiencing at least one hot flash. We also tested the potential moderating role of neuroticism.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a secondary analysis of data from Midlife Development in the United States (MIDUS), and analyzed data from an 8\u2010day self\u2010report diary phase. Participants were 130 women aged 42 to 60 who reported experiencing at least 1 day of hot flashes in the 8\u2010day period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Results showed that on days when hot flash was reported, daily stress was significantly associated with hot flash severity on both the between\u2010 and within\u2010person levels. However, the relationship between daily stress and hot flash\n                      <jats:italic>occurrence<\/jats:italic>\n                      was not significant. Neuroticism did not significantly moderate any of the relationships.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      These findings indicate that among women who experienced hot flashes, on days when hot flash was reported, higher perceived stress is associated with higher hot flash severity; more importantly, hot flash severity is higher\n                      <jats:italic>on days when stress is higher<\/jats:italic>\n                      . If the within\u2010person association is replicated in future studies, these findings may have implications for therapeutically targeting stress as a potential avenue for alleviating hot flashes.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jclp.70201","type":"journal-article","created":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T08:47:13Z","timestamp":1785833233000},"page":"1874-1885","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Relationship Between Daily Stress and Hot Flashes in Women of Menopausal Age"],"prefix":"10.1002","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2764-5024","authenticated-orcid":false,"given":"Yiqing Alice","family":"Fan","sequence":"first","affiliation":[{"name":"American University Washington, D.C. 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