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No differences were found in the 16,000 \u00d7 g pellets containing mitochondria, membranes, and granules and representing 96% of total SOD activity in PMNs and monocytes but only 48% total SOD activity in alveolar macrophages. The 100,000 \u00d7 g microsomal pellet of alveolar macrophages contained 8% of total SOD activity and two\u2010five times more activity than the respective fractions from monocytes and PMNs. However, there was 70 times more SOD in the 100,000 \u00d7 g supernatant from alveolar macrophages containing 44% of total enzyme activity than in the same fraction of PMNs and monocytes containing less than 2% total SOD activity. SOD activity is mainly located in the 16,000 \u00d7 g particulate fraction of PMN and monocytes but more equally distributed between the particulate fractions and cytosol of alveolar macrophages.<\/jats:p>","DOI":"10.1002\/jcp.1040870310","type":"journal-article","created":{"date-parts":[[2005,2,26]],"date-time":"2005-02-26T02:53:33Z","timestamp":1109386413000},"page":"345-355","source":"Crossref","is-referenced-by-count":20,"title":["A comparative study of superoxide dismutase activity in polymorphonuclear leukocytes, monocytes, and alveolar macrophages of the guinea pig"],"prefix":"10.1002","volume":"87","author":[{"given":"Manfred","family":"Rister","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"Baehner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,2,4]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000152594"},{"key":"e_1_2_1_3_1","first-page":"77","article-title":"Isolation of mononuclear cells and granulocytes from human blood","volume":"97","author":"B\u00f6yum A.","year":"1967","journal-title":"Scand. 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