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Echocardiographic analysis of 4111 subjects in the CARDIA Study. Coronary artery risk development in (Young) adults","volume":"92","author":"Maron","year":"1995","journal-title":"Circulation"},{"key":"10.1002\/jcp.25424-BIB0126|jcp25424-cit-0126","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1161\/CIRCULATIONAHA.106.174287","article-title":"Contemporary definitions and classification of the cardiomyopathies: An American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention","volume":"113","author":"Maron","year":"2006","journal-title":"Circulation"},{"key":"10.1002\/jcp.25424-BIB0127|jcp25424-cit-0127","first-page":"295","article-title":"Hypertrophic cardiomyopathy: How do mutations lead to disease","volume":"102","author":"Marsiglia","year":"2014","journal-title":"Arq Bras 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localization","volume":"22","author":"Mavroidis","year":"2008","journal-title":"FASEB J"},{"key":"10.1002\/jcp.25424-BIB0134|jcp25424-cit-0134","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1172\/JCI62862","article-title":"Genetic mutations and mechanisms in dilated cardiomyopathy","volume":"123","author":"McNally","year":"2015","journal-title":"J Clin Invest"},{"key":"10.1002\/jcp.25424-BIB0135|jcp25424-cit-0135","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.jacc.2009.04.029","article-title":"Phenotypic heterogeneity of sarcomeric gene mutations: A matter of gain and loss","volume":"54","author":"Mestroni","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"10.1002\/jcp.25424-BIB0136|jcp25424-cit-0136","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1038\/ejhg.2012.173","article-title":"Novel mutations in the sarcomeric protein myopalladin in patients with dilated 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between nebulin-like motifs and thin filament regulatory proteins","volume":"278","author":"Ogut","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1002\/jcp.25424-BIB0156|jcp25424-cit-0156","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1006\/jmcc.2000.1204","article-title":"Inherited and de novo mutations in the cardiac actin gene cause hypertrophic cardiomyopathy","volume":"32","author":"Olson","year":"2000","journal-title":"J Mol Cell Cardiol"},{"key":"10.1002\/jcp.25424-BIB0157|jcp25424-cit-0157","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1161\/hc0402.102930","article-title":"Metavinculin mutations alter actin interaction in dilated cardiomyopathy","volume":"105","author":"Olson","year":"2002","journal-title":"Circulation"},{"key":"10.1002\/jcp.25424-BIB0158|jcp25424-cit-0158","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1126\/science.280.5364.750","article-title":"Actin mutations in dilated cardiomyopathy, a heritable form of heart 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