{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T10:18:57Z","timestamp":1760523537460,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,8,3]],"date-time":"2017-08-03T00:00:00Z","timestamp":1501718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal Cellular Physiology"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec><jats:label\/><jats:p>The use of stem cells in cell\u2010based therapy is an emerging concept for the treatment of ear disorders. Tympanic membrane perforation (TMP) and inner ear disorders are some of the most commonly presented otologic disorders that can benefit from advances in cell\u2010based therapy. Studies have already demonstrated that stem cell\u2010based therapy can potentially be an effective treatment modality for acute and chronic TMP. Recent studies have also shown promise in application of cell\u2010based approach to treat inner ear dysfunction. In this perspective, we will discuss the recent advancements regarding the use of cell\u2010based therapy for ear disorders.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcp.26048","type":"journal-article","created":{"date-parts":[[2017,6,13]],"date-time":"2017-06-13T12:02:50Z","timestamp":1497355370000},"page":"1823-1824","source":"Crossref","is-referenced-by-count":3,"title":["A perspective on stem cell therapy for ear disorders"],"prefix":"10.1002","volume":"233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0894-237X","authenticated-orcid":false,"given":"Rahul","family":"Mittal","sequence":"first","affiliation":[{"name":"Department of Otolaryngology University of Miami Miller School of Medicine Miami Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyunseo D.","family":"Jung","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Miami Miller School of Medicine Miami Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeenu","family":"Mittal","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Miami Miller School of Medicine Miami Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrien A.","family":"Eshraghi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology University of Miami Miller School of Medicine Miami Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,8,3]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0954411916666109"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11415"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-016-1021-1"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599816636845"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2016.1261411"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.2217\/rme.13.32"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12298"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm925"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/sctm.16-0032"},{"key":"e_1_2_2_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.25631"},{"key":"e_1_2_2_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/1084713812440336"},{"key":"e_1_2_2_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.03.035"},{"key":"e_1_2_2_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016480701762508"},{"key":"e_1_2_2_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2017.04.002"},{"key":"e_1_2_2_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4449"}],"container-title":["Journal of Cellular Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjcp.26048","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcp.26048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T14:24:50Z","timestamp":1696688690000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcp.26048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,3]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1002\/jcp.26048"],"URL":"https:\/\/doi.org\/10.1002\/jcp.26048","archive":["Portico"],"relation":{},"ISSN":["0021-9541","1097-4652"],"issn-type":[{"type":"print","value":"0021-9541"},{"type":"electronic","value":"1097-4652"}],"subject":[],"published":{"date-parts":[[2017,8,3]]}}}