{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T22:05:40Z","timestamp":1773266740105,"version":"3.50.1"},"reference-count":198,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,12,26]],"date-time":"2017-12-26T00:00:00Z","timestamp":1514246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2017,12,26]],"date-time":"2017-12-26T00:00:00Z","timestamp":1514246400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal Cellular Physiology"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec>\n                    <jats:label\/>\n                    <jats:p>During embryo implantation, crosstalk between the endometrial epithelium and the blastocyst, especially the trophoblasts, is a prerequisite for successful implantation. During this crosstalk, various molecular and functional changes occur to promote synchrony between the embryo and the endometrium as well as the uterine cavity microenvironment. In the past few years, growing evidence has shown that endometrium\u2010derived exosomes play pivotal roles in the embryonic\u2010maternal crosstalk during implantation, although the exact mechanism of this crosstalk has yet to be determined. The presence of metalloproteinases has been reported in endometrium\u2010derived exosomes, implying the importance of these enzymes in exosome\u2010based crosstalk. Thus, in this review, we describe the potential roles of the metalloproteinases of endometrium\u2010derived exosomes in promoting embryo attachment and implantation. This study could provide a better understanding of the potential roles of exosomal metalloproteinases in embryo implantation and pave the way for developing novel exosome\u2010based regulatory agents to support early pregnancy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcp.26259","type":"journal-article","created":{"date-parts":[[2017,11,8]],"date-time":"2017-11-08T07:02:54Z","timestamp":1510124574000},"page":"4530-4545","source":"Crossref","is-referenced-by-count":43,"title":["Potential roles of metalloproteinases of endometrium\u2010derived exosomes in embryo\u2010maternal crosstalk during implantation"],"prefix":"10.1002","volume":"233","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5010-0013","authenticated-orcid":false,"given":"Zeinab","family":"Latifi","sequence":"first","affiliation":[{"name":"Animal Resource Science Center Graduate School of Agricultural and Life Sciences The University of Tokyo Ibaraki Japan"},{"name":"Stem Cell and Regenerative Medicine Institute Tabriz University of Medical Sciences Tabriz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5712-5336","authenticated-orcid":false,"given":"Amir","family":"Fattahi","sequence":"additional","affiliation":[{"name":"Department of Reproductive Biology Faculty of Advanced Medical Sciences Tabriz University of Medical Sciences Tabriz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Ranjbaran","sequence":"additional","affiliation":[{"name":"Women's Reproductive Health Research Center Tabriz University of Medical Sciences Tabriz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2654-3965","authenticated-orcid":false,"given":"Hamid Reza","family":"Nejabati","sequence":"additional","affiliation":[{"name":"Women's Reproductive Health Research Center Tabriz University of Medical Sciences Tabriz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3798-3560","authenticated-orcid":false,"given":"Kazuhiko","family":"Imakawa","sequence":"additional","affiliation":[{"name":"Animal Resource Science Center Graduate School of Agricultural and Life Sciences The University of Tokyo Ibaraki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja109972p"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.11-184663"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3810"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1725"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2012.07.023"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dei242"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1071\/RDv27n1Ab108"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1502590112"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.83.5.1783"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(90)90694-A"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.1.00283"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1927"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1530\/reprod\/120.1.125"},{"key":"e_1_2_7_15_1","first-page":"24","article-title":"Membrane type 1\u2010matrix metalloproteinase: Substrate diversity in pericellular proteolysis","author":"Barbolina M. V.","year":"2008","journal-title":"Elsevier"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/8379256"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M010135200"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep40476"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/plac.1999.0447"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1262\/jrd.2013-002"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1548"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/8.3.237"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep011"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.6.15.1281457"},{"key":"e_1_2_7_25_1","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1093\/molehr\/8.4.375","article-title":"Hormonal and embryonic regulation of chemokines IL\u20108, MCP\u20101 and RANTES in the human endometrium during the window of implantation","volume":"8","author":"Caballero\u2010Campo P.","year":"2002","journal-title":"Human Reproduction"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a135955"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2010.278"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1021350718226"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.1.01020"},{"key":"e_1_2_7_30_1","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.ijdevneu.2006.09.301","article-title":"The role of metalloproteinase ADAM10 in the embryonic visual system of Xenopus laevis","volume":"8","author":"Chen Y.","year":"2006","journal-title":"International Journal of Developmental Neuroscience"},{"key":"e_1_2_7_31_1","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.bbapap.2011.09.003","article-title":"Regulation of matrix metalloproteinases activity studied in human endometrium as a paradigm of cyclic tissue breakdown and regeneration","volume":"1824","author":"Chevronnay H. P. G.","year":"2012","journal-title":"Biochimica Et Biophysica Acta (BBA)\u2010Proteins and Proteomics"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4773(02)00342-8"},{"key":"e_1_2_7_33_1","first-page":"69","article-title":"Extracellular vesicles shuffling intercellular messages: For good or for bad","volume":"35","author":"Cicero A. L.","year":"2015","journal-title":"Clinical & Experimental Metastasis"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0967199400001660"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2008.00963.x"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.modgep.2004.04.003"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms14035338"},{"key":"e_1_2_7_38_1","first-page":"383","article-title":"Expression of alpha 2\u2010macroglobulin receptor\/low density lipoprotein receptor\u2010related protein and the 39\u2010kd receptor\u2010associated protein in human trophoblasts","volume":"144","author":"Coukos G.","year":"1994","journal-title":"The American Journal of Pathology"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.2174\/138161209788682442"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-13-0474"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1997.00751.x"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719115574344"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD14452"},{"key":"e_1_2_7_44_1","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1242\/dev.120.5.1071","article-title":"Heparin\u2010binding EGF\u2010like growth factor gene is induced in the mouse uterus temporally by the blastocyst solely at the site of its apposition: A possible ligand for interaction with blastocyst EGF\u2010receptor in implantation","volume":"120","author":"Das S. K.","year":"1994","journal-title":"Development\u2010Cambridge"},{"key":"e_1_2_7_45_1","first-page":"44","article-title":"Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in the mouse uterus during the peri\u2010implantation period","volume":"21","author":"Das S. K.","year":"1997","journal-title":"Genesis"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.77.5.863"},{"key":"e_1_2_7_47_1","first-page":"4468","article-title":"Selective localization of matrix metalloproteinase 9, beta1 integrins, and human lymphocyte antigen class I molecules on membrane vesicles shed, by 8701\u2010BC breast carcinoma cells","volume":"58","author":"Dolo V.","year":"1998","journal-title":"Cancer Research"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2008.08.001"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M306736200"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0143-4004(03)00148-6"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1081277"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dml048"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.2741\/Fleming"},{"key":"e_1_2_7_54_1","first-page":"4539","article-title":"Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms","volume":"54","author":"Fox S. B.","year":"1994","journal-title":"Cancer Research"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0093-691X(98)00095-8"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0093-691X(03)00116-X"},{"key":"e_1_2_7_57_1","first-page":"2138","article-title":"Differential expression of emmprin in normal and ulcerated corneas: Role in epithelio\u2010Stromal interactions and MMP induction","volume":"46","author":"Gabison E.","year":"2005","journal-title":"Investigative Ophthalmology & Visual Science"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.12703"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.27.17216"},{"key":"e_1_2_7_60_1","first-page":"1101","article-title":"Characterization of the mechanisms by which gelatinase A, neutrophil collagenase, and membrane\u2010type metalloproteinase MMP\u201014 recognize collagen I and enzymatically process the two \u03b1\u2010chains","volume":"368","author":"Gioia M.","year":"2007","journal-title":"Journal of Biological Chemistry"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.02.022"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(03)00341-5"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1016199109"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2009.11.012"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/2.9.685"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.115.134890"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1053\/plac.1998.0385"},{"key":"e_1_2_7_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0143-4004(81)80021-5"},{"key":"e_1_2_7_69_1","unstructured":"Guli\u0107T La\u0161karinG Red\u017eovi\u0107A RukavinaD. (2011). Expression of HSP90 family members and their receptors at maternal fetal interface of early healthy human pregnancy. 2011 Annual meeting of the Croatian immunological Society. Rabac Croatia: Croatian Immunology Society. p 45\u201345."},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2008.10.012"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.21923"},{"key":"e_1_2_7_72_1","first-page":"16297","article-title":"Embryo implantation: Shedding light on the roles of ovarian hormones, cytokines and growth factors in the implantation process","volume":"11","author":"Hamid H. Y.","year":"2012","journal-title":"African Journal of Biotechnology"},{"key":"e_1_2_7_73_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/11.21.2615"},{"key":"e_1_2_7_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2013.01.011"},{"key":"e_1_2_7_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80064-1"},{"key":"e_1_2_7_76_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.02-1190"},{"key":"e_1_2_7_77_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1451806"},{"key":"e_1_2_7_78_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.115.132977"},{"key":"e_1_2_7_79_1","doi-asserted-by":"publisher","DOI":"10.1177\/002215549804600211"},{"key":"e_1_2_7_80_1","doi-asserted-by":"publisher","DOI":"10.2741\/Hussain1"},{"key":"e_1_2_7_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2004.08.001"},{"key":"e_1_2_7_82_1","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1071\/RDv16n1Ab137","article-title":"137 the effect of ANTI\u2010CD44 on embryo implantation in rabbits","volume":"16","author":"Illera M.","year":"2003","journal-title":"Reproduction, Fertility, and Development"},{"key":"e_1_2_7_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2006.09.014"},{"key":"e_1_2_7_84_1","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.rbmo.2016.07.011","article-title":"Apolipoprotein A1 and heterogeneous nuclear ribonucleoprotein E1 implicated in the regulation of embryo implantation by inhibiting lipid peroxidation","volume":"33","author":"Jia J.","year":"2016","journal-title":"Reproductive BioMedicine Online"},{"key":"e_1_2_7_85_1","first-page":"629","article-title":"Expression of interleukin 8 in mouse endometrium during early pregnancy and its effect on blastocyst implantation","volume":"28","author":"Jiang W.","year":"2004","journal-title":"Chinese Journal of Anatomy"},{"key":"e_1_2_7_86_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-0240"},{"key":"e_1_2_7_87_1","first-page":"305990","article-title":"Embryonic stem cell\u2010derived exosomes promote endogenous repair mechanisms and enhance cardiac function following myocardial infarction","volume":"115","author":"Khan M.","year":"2015","journal-title":"Circulation Research: CIRCRESAHA"},{"key":"e_1_2_7_88_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.1999.tb01128.x"},{"key":"e_1_2_7_89_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0570fje"},{"key":"e_1_2_7_90_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2006.47.4.558"},{"key":"e_1_2_7_91_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD04110"},{"key":"e_1_2_7_92_1","first-page":"327","article-title":"Cellular and molecular events during oocyte maturation in mammals: Molecules of cumulus\u2010oocyte complex matrix and signalling pathways regulating meiotic progression","volume":"63","author":"Kimura N.","year":"2006","journal-title":"Society of Reproduction and Fertility Supplement"},{"key":"e_1_2_7_93_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0590095"},{"key":"e_1_2_7_94_1","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1242\/jcs.109.5.953","article-title":"MT\u2010MMP, the cell surface activator of proMMP\u20102 (pro\u2010gelatinase A), is expressed with its substrate in mouse tissue during embryogenesis","volume":"109","author":"Kinoh H.","year":"1996","journal-title":"Journal of Cell Science"},{"key":"e_1_2_7_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(02)03654-2"},{"key":"e_1_2_7_96_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12958-016-0207-4"},{"key":"e_1_2_7_97_1","doi-asserted-by":"crossref","unstructured":"Koot Y. van Hooff S. Boomsma C. van Leenen D. Koerkamp M. Goddijn M. \u2026Macklon N.(2014). The endometrial gene expression signature of recurrent implantation failure after IVF;. Oxford Univ Press Great Clarendon St Oxford Ox2 6dp England 196\u2013196.","DOI":"10.1038\/srep19411"},{"key":"e_1_2_7_98_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a011213"},{"key":"e_1_2_7_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.03.045"},{"key":"e_1_2_7_100_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.148.3.615"},{"key":"e_1_2_7_101_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0152921"},{"key":"e_1_2_7_102_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/971907"},{"key":"e_1_2_7_103_1","doi-asserted-by":"publisher","DOI":"10.1515\/BC.2002.118"},{"key":"e_1_2_7_104_1","first-page":"163","article-title":"Latent\u2010TGF\u2010\u03b2: An overview","volume":"219","author":"Lawrence D. A.","year":"2001","journal-title":"Molecular Biology of the Cell"},{"key":"e_1_2_7_105_1","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E08-01-0016"},{"key":"e_1_2_7_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.02.189"},{"key":"e_1_2_7_107_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-08-355818"},{"key":"e_1_2_7_108_1","doi-asserted-by":"publisher","DOI":"10.4161\/cc.8.22.9956"},{"key":"e_1_2_7_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2008.10.016"},{"key":"e_1_2_7_110_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/114.3.402"},{"key":"e_1_2_7_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/0925-4773(92)90065-R"},{"key":"e_1_2_7_112_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0500918102"},{"key":"e_1_2_7_113_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/13.6.1645"},{"key":"e_1_2_7_114_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-2713"},{"key":"e_1_2_7_115_1","first-page":"81","article-title":"Transforming growth factor\u2010Beta 1 (TGF\u2010B1) liberation from its latent complex during embryo implantation and its regulation by estradiol in mouse 1","volume":"84","author":"Maurya V. K.","year":"2013","journal-title":"Biology of Reproduction"},{"key":"e_1_2_7_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2009.09.008"},{"key":"e_1_2_7_117_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.318774"},{"key":"e_1_2_7_118_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1222387110"},{"key":"e_1_2_7_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.domaniend.2011.09.004"},{"key":"e_1_2_7_120_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2011.04158.x"},{"key":"e_1_2_7_121_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cr.7290227"},{"key":"e_1_2_7_122_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0058502"},{"key":"e_1_2_7_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2009.05.011"},{"key":"e_1_2_7_124_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0023894"},{"key":"e_1_2_7_125_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.4.2446"},{"key":"e_1_2_7_126_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2120"},{"key":"e_1_2_7_127_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2125"},{"key":"e_1_2_7_128_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/der027"},{"key":"e_1_2_7_129_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.25.1.389-402.2005"},{"key":"e_1_2_7_130_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri1418"},{"key":"e_1_2_7_131_1","first-page":"57","volume-title":"Membrane\u2010type matrix metalloproteinase and inhibitor expression in sheep embryos and uterus","author":"Paul KB.","year":"2001"},{"key":"e_1_2_7_132_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0531.2010.01681.x"},{"key":"e_1_2_7_133_1","first-page":"1","article-title":"Deregulation of the endometrial stromal cell secretome precedes embryo implantation failure","author":"Peter Durairaj R. R.","year":"2017","journal-title":"MHR: Basic Science of Reproductive Medicine"},{"key":"e_1_2_7_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0143-4004(83)80043-5"},{"key":"e_1_2_7_135_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.034561"},{"key":"e_1_2_7_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2007.07.001"},{"key":"e_1_2_7_137_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.122.2.637"},{"key":"e_1_2_7_138_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404132"},{"key":"e_1_2_7_139_1","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1071\/SRB03Ab110","article-title":"110. Matrix metalloproteinase\u20102 (MMP\u20102) in the murine uterine tissue during early embryo implantation","volume":"15","author":"Roy T. K.","year":"2003","journal-title":"Reproduction, Fertility and Development"},{"key":"e_1_2_7_140_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M311569200"},{"key":"e_1_2_7_141_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200408028"},{"key":"e_1_2_7_142_1","doi-asserted-by":"publisher","DOI":"10.1071\/SRB09Abs005"},{"key":"e_1_2_7_143_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.12450"},{"key":"e_1_2_7_144_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.12450"},{"key":"e_1_2_7_145_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1015407012559"},{"key":"e_1_2_7_146_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068451"},{"key":"e_1_2_7_147_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0098667"},{"key":"e_1_2_7_148_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M408804200"},{"key":"e_1_2_7_149_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-12-204"},{"key":"e_1_2_7_150_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1039703"},{"key":"e_1_2_7_151_1","first-page":"253","article-title":"Membrane\u2010type 1 matrix metalloproteinase and cell migration","author":"Seiki M.","year":"2003","journal-title":"Portland Press Limited"},{"key":"e_1_2_7_152_1","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201200458"},{"key":"e_1_2_7_153_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2017.05.027"},{"key":"e_1_2_7_154_1","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1177\/1933719116667490","article-title":"Implantation failure is associated with increased \u03b1\u2010Inhibin and \u03b2\u2010Glycan gene expression in secretory phase endometrium: Nested case\u2010Control study of infertile women undergoing IVF\/Fresh embryo transfer","volume":"24","author":"Silveira C. O.","year":"2016","journal-title":"Reproductive Sciences"},{"key":"e_1_2_7_155_1","doi-asserted-by":"publisher","DOI":"10.1053\/beog.2000.0121"},{"key":"e_1_2_7_156_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1230693100"},{"key":"e_1_2_7_157_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1800"},{"key":"e_1_2_7_158_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2006.00443.x"},{"key":"e_1_2_7_159_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10974-015-9414-4"},{"key":"e_1_2_7_160_1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/978-1-4612-1548-6_2","volume-title":"Embryo implantation","author":"Spandorfer S.","year":"1999"},{"key":"e_1_2_7_161_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-2-59"},{"key":"e_1_2_7_162_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2006.01987.x"},{"key":"e_1_2_7_163_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.10.5331"},{"key":"e_1_2_7_164_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201205176"},{"key":"e_1_2_7_165_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod59.5.1207"},{"key":"e_1_2_7_166_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-10-249847"},{"key":"e_1_2_7_167_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M407186200"},{"key":"e_1_2_7_168_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0305862101"},{"key":"e_1_2_7_169_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0143-4004(98)90097-2"},{"key":"e_1_2_7_170_1","doi-asserted-by":"publisher","DOI":"10.1038\/cmi.2014.42"},{"key":"e_1_2_7_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2014.03.004"},{"key":"e_1_2_7_172_1","doi-asserted-by":"publisher","DOI":"10.1159\/000066963"},{"key":"e_1_2_7_173_1","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1210\/er.2014-1046","article-title":"Soluble ligands and their receptors in human embryo development and implantation","volume":"36","author":"Thouas G. A.","year":"2014","journal-title":"Endocrine Reviews"},{"key":"e_1_2_7_174_1","first-page":"453","article-title":"Expressions of epidermal growth factor family and its receptor in hepatocellular carcinoma cell lines: Relationship to cell proliferation","volume":"14","author":"Tohruhisaka H. Y.","year":"1999","journal-title":"International Journal of Oncology"},{"key":"e_1_2_7_175_1","first-page":"5151\u2013","article-title":"The role of ADAM10 in retinal development","volume":"54","author":"Toonen J.","year":"2013","journal-title":"Investigative Ophthalmology & Visual Science"},{"key":"e_1_2_7_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2004.12.005"},{"key":"e_1_2_7_177_1","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1016\/j.ajpath.2011.11.014","article-title":"MMP\u201014 is expressed in preeclamptic placentas and mediates release of soluble endoglin","volume":"180","author":"Tu'uhevaha J.","year":"2012","journal-title":"The American Journal of Pathology"},{"key":"e_1_2_7_178_1","doi-asserted-by":"publisher","DOI":"10.3390\/genes4020152"},{"key":"e_1_2_7_179_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1596"},{"key":"e_1_2_7_180_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.113.114876"},{"key":"e_1_2_7_181_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1808"},{"key":"e_1_2_7_182_1","first-page":"391","article-title":"Biology of implantation","volume":"1","author":"Weitlauf H.","year":"1994","journal-title":"The Physiology of Reproduction"},{"key":"e_1_2_7_183_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199906103402304"},{"key":"e_1_2_7_184_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198807283190401"},{"key":"e_1_2_7_185_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0378(91)90008-E"},{"key":"e_1_2_7_186_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.5.8.1850705"},{"key":"e_1_2_7_187_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-78797-6"},{"key":"e_1_2_7_188_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.64.207"},{"key":"e_1_2_7_189_1","doi-asserted-by":"publisher","DOI":"10.3402\/jev.v4.27066"},{"key":"e_1_2_7_190_1","first-page":"824","article-title":"Effect of ephrin\u2010A1\/EphA2 on invasion of trophoblastic cells","volume":"31","author":"Yang Y.","year":"2011","journal-title":"Journal of Huazhong University of Science and Technology\u2013Medical Sciences"},{"key":"e_1_2_7_191_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod67.4.1165"},{"key":"e_1_2_7_192_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2013.06.010"},{"key":"e_1_2_7_193_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.256644"},{"key":"e_1_2_7_194_1","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.22391"},{"key":"e_1_2_7_195_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod62.1.85"},{"key":"e_1_2_7_196_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-013-1685-8"},{"key":"e_1_2_7_197_1","doi-asserted-by":"crossref","first-page":"28881","DOI":"10.18632\/oncotarget.7591","article-title":"Betacellulin induces Slug\u2010mediated down\u2010regulation of E\u2010cadherin and cell migration in ovarian cancer cells","volume":"7","author":"Zhao J.","year":"2016","journal-title":"Oncotarget"},{"key":"e_1_2_7_198_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.24204"},{"key":"e_1_2_7_199_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.060037197"}],"container-title":["Journal of Cellular Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjcp.26259","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcp.26259","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jcp.26259","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcp.26259","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T10:59:03Z","timestamp":1773053943000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcp.26259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,26]]},"references-count":198,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1002\/jcp.26259"],"URL":"https:\/\/doi.org\/10.1002\/jcp.26259","archive":["Portico"],"relation":{},"ISSN":["0021-9541","1097-4652"],"issn-type":[{"value":"0021-9541","type":"print"},{"value":"1097-4652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,26]]}}}