{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T15:35:55Z","timestamp":1778600155090,"version":"3.51.4"},"reference-count":60,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,8,2]],"date-time":"2018-08-02T00:00:00Z","timestamp":1533168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Council of Scientific & Industrial Research (CSIR), India","award":["09\/013(0339)\/2010-EMR-I"],"award-info":[{"award-number":["09\/013(0339)\/2010-EMR-I"]}]},{"name":"Department of Science and Technology, New Delhi, India","award":["SR\/50\/AS-14\/2012"],"award-info":[{"award-number":["SR\/50\/AS-14\/2012"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Cellular Physiology"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:p>Specific phase relation of serotonin and dopamine modulate the hypothalamo\u2013hypophyseal\u2013gonadal axis as well as photosexual responses in Japanese quail, but the effect of these specific phase relations on testicular activity and steroidogenesis is not yet been investigated. We hypothesized that temporal phase relation induced alteration in local testicular gonadotropin\u2010releasing hormone (GnRH)\u2013Gonadotropin\u2010inhibitory hormone (GnIH) and their receptor system may modulate the testicular activity and steroidogenesis through local (paracrine and autocrine) action. To validate this hypothesis, we have checked the alterations in the expression of gonadotropin\u2010releasing hormone receptor (GnRH\u2010R), gonadotropin\u2010inhibitory hormone receptor (GnIH\u2010R) messenger RNA (mRNA), growth hormone receptor (GH\u2010R), proliferating cell nuclear antigen (PCNA), cell communication and gap junctional proteins (14\u20103\u20103 and connexin\u201043 [Cnx\u201043]), steroidogenic factor\u20101 (SF\u20101), steroidogenic acute regulatory\u00a0(StAR) protein, steroidogenic enzyme (3\u03b2\u2010hydroxysteroid dehydrogenase [3\u03b2\u2010HSD]) in testis as well as androgen receptor (AR) in testis and epididymis of control, 8\u2010, and 12\u2010hr quail. Experimental findings clearly indicate the increased expression of GnIH\u2010R mRNA and suppression of GnRH\u2010R, GH\u2010R, PCNA, 14\u20103\u20103, Cnx\u201043, SF\u20101, StAR, 3\u03b2\u2010HSD in testis as well as AR in testis and epididymis in 8\u2010hr quail, while 12\u2010hr quail exhibited the opposite results that is significantly decreased expression of GnIH\u2010R mRNA and increased expression of GnRH\u2010R, GH\u2010R, PCNA, 14\u20103\u20103, Cnx\u201043, SF\u20101, StAR, 3\u03b2\u2010HSD in testis as well as AR in testis and epididymis. The significantly increased intratesticular testosterone has been observed in the 12\u2010hr quail while, 8\u2010hr quail showed opposite result. Hence, it can be concluded that 12\u2010hr quail showed significantly increased testicular activity and steroidogenesis while opposite pattern was observed in 8\u2010hr quail.<\/jats:p>","DOI":"10.1002\/jcp.27104","type":"journal-article","created":{"date-parts":[[2018,8,7]],"date-time":"2018-08-07T04:35:26Z","timestamp":1533616526000},"page":"2866-2879","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Specific neural phase relation of serotonin and dopamine modulate the testicular activity in Japanese quail"],"prefix":"10.1002","volume":"234","author":[{"given":"Somanshu","family":"Banerjee","sequence":"first","affiliation":[{"name":"Department of Zoology Banaras Hindu University Varanasi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7135-3450","authenticated-orcid":false,"given":"Chandra Mohini","family":"Chaturvedi","sequence":"additional","affiliation":[{"name":"Department of Zoology Banaras Hindu University Varanasi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8,2]]},"reference":[{"key":"e_1_2_9_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2006.03.005"},{"key":"e_1_2_9_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0968-0004(92)90339-B"},{"key":"e_1_2_9_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2015.08.016"},{"key":"e_1_2_9_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2017.09.005"},{"key":"e_1_2_9_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2017.11.034"},{"key":"e_1_2_9_1_7_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.129155"},{"key":"e_1_2_9_1_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/002215540004800608"},{"key":"e_1_2_9_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2007.10.003"},{"key":"e_1_2_9_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(99)90038-2"},{"key":"e_1_2_9_1_11_1","first-page":"pp. 475","volume-title":"The pharmacological basis of therapeutics","author":"Bianchine J. 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