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Multiple factors conspire to impair closure of chronic wounds such as diabetic foot ulcers, venous leg ulcers and pressure wounds. Despite deep mechanistic understanding of microRNA (miRNA) biogenesis and function, the translational potential of these small genetic molecules has not been exploited to promote wound repair. In this review, I focus on miRNAs whose importance for wound healing stems from their impact on epidermal keratinocyte behaviour. These include miR\u201021\u20105p, miR\u201031\u20105p, miR\u2010132\u20103p, miR\u201019b, miR\u201020a, miR\u2010184, miR\u2010129\u20105p and miR\u2010335\u20105p which regulate diverse aspect of keratinocyte biology such as migration, proliferation, differentiation, inflammation and wound closure. A combinatorial approach where two or more miRNA mimics targeting distinct but complementary wound healing processes is proposed as this may enhance wound repair more effectively than any single miRNA mimic alone.<\/jats:p>","DOI":"10.1002\/jcp.30485","type":"journal-article","created":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T10:38:12Z","timestamp":1624444692000},"page":"8050-8059","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["MiR equal than others: MicroRNA enhancement for cutaneous wound healing"],"prefix":"10.1002","volume":"236","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0252-1152","authenticated-orcid":false,"given":"Kehinde","family":"Ross","sequence":"first","affiliation":[{"name":"School of Pharmacy and Biomolecular Science Liverpool John Moores University Liverpool England 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