{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T18:33:35Z","timestamp":1773167615347,"version":"3.50.1"},"reference-count":45,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T00:00:00Z","timestamp":1716768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Cellular Physiology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Syntaxin of plant (SYP) plays a crucial role in SNARE\u2010mediated membrane trafficking during endocytic and secretory pathways, contributing to the regulation and execution of plant immunity against pathogens. Verticillium wilt is among the most destructive fungal diseases affecting cotton worldwide. However, information regarding SYP family genes in cotton is scarce. Through genome\u2010wide identification and transcriptome profiling, we identified <jats:italic>GhSYP121<\/jats:italic>, a Qa SNARE gene in <jats:italic>Gossypium hirsutum<\/jats:italic>. <jats:italic>GhSYP121<\/jats:italic> is notably induced by <jats:italic>Verticillium dahliae<\/jats:italic>, the causal agent of Verticillium wilt in cotton, and acts as a negative regulator of defense against <jats:italic>V. dahliae<\/jats:italic>. This is evidenced by the reduced resistance of <jats:italic>GhSYP121<\/jats:italic>\u2010deficient cotton and the increased susceptibility of <jats:italic>GhSYP121<\/jats:italic>\u2010overexpressing lines. Furthermore, the activation of the salicylic acid (SA) pathway by <jats:italic>V. dahliae<\/jats:italic> is inversely correlated with the expression level of <jats:italic>GhSYP121<\/jats:italic>. GhSYP121 interacts with its cognate SNARE component, GhSNAP33, which is required for the penetration resistance against <jats:italic>V. dahliae<\/jats:italic> in cotton. Collectively, GhSYP121, as a member of the cotton SNARE complex, is involved in regulating the SA pathway during plant defense against <jats:italic>V. dahliae<\/jats:italic>. This finding enhances our understanding of the potential role of GhSYP121 in these distinct pathways that contribute to plant defense against <jats:italic>V. dahliae<\/jats:italic> infection.<\/jats:p>","DOI":"10.1002\/jcp.31329","type":"journal-article","created":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T12:24:27Z","timestamp":1716812667000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cotton SNARE complex component GhSYP121 regulates salicylic acid signaling during defense against <i>Verticillium dahliae<\/i>"],"prefix":"10.1002","volume":"239","author":[{"given":"Linying","family":"Gao","sequence":"first","affiliation":[{"name":"College of Science China Agricultural University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yakun","family":"Pei","sequence":"additional","affiliation":[{"name":"College of Science China Agricultural University Beijing 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