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Ondansetron and granisetron co\u2010treatment increased unbound platinum exposure compared to palonosetron co\u2010treatment, suggesting that palonosetron may be a preferred 5\u2010HT<jats:sub>3<\/jats:sub>A to reduce the risk of cisplatin\u2010induced kidney injury.<\/jats:p>","DOI":"10.1002\/jcph.6177","type":"journal-article","created":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T07:50:45Z","timestamp":1734940245000},"page":"763-778","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Population Pharmacokinetic Model of Platinum Disposition in Cancer Patients Receiving Cisplatin and Randomized to 5\u2010HT<sub>3<\/sub> Antagonist Antiemetic Drugs"],"prefix":"10.1002","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0297-199X","authenticated-orcid":false,"given":"Lauren E.","family":"Thompson","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Sciences, Skaggs School of 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