{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T15:41:16Z","timestamp":1791819676677,"version":"4.3.4"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Hellenic Association for the Study of the Liver"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although malnutrition and sarcopenia are prevalent in cirrhosis, their impact on outcomes following liver transplantation is not well documented.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The associations of nutritional status and sarcopenia with post\u2010transplant infections, requirement for mechanical ventilation, intensive care (ICU) and hospital stay, and 1\u2009year mortality were assessed in 232 consecutive transplant recipients. Nutritional status and sarcopenia were assessed using the Royal Free Hospital\u2010Global Assessment (RFH\u2010GA) tool and the L3\u2010psoas muscle index (L3\u2010PMI) on CT, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A wide range of RFH\u2010SGA and L3\u2010PMI were observed within similar Model for End\u2010stage Liver Disease (MELD) sub\u2010categories. Malnutrition and sarcopenia were independent predictors of all outcomes. Post\u2010transplant infections were associated with MELD (OR\u2009=\u20091.055, 95%CI\u2009=\u20091.002\u20131.11) and severe malnutrition (OR\u2009=\u20096.55, 95%CI\u2009=\u20091.99\u201321.5); ventilation\u2009&gt;\u200924\u2009h with MELD (OR\u2009=\u20091.1, 95%CI\u2009=\u20091.036\u20131.168), severe malnutrition (OR\u2009=\u20098.5, 95%CI\u2009=\u20091.48\u201348.87) and suboptimal donor liver (OR\u2009=\u20092.326, 95%CI\u2009=\u20091.056\u20135.12); ICU stay\u2009&gt;\u20095\u2009days, with age (OR\u2009=\u20091.054, 95%CI\u2009=\u20091.004\u20131.106), MELD (OR\u2009=\u20091.137, 95%CI\u2009=\u20091.057\u20131.223) and severe malnutrition (OR\u2009=\u20097.46, 95%CI\u2009=\u20091.57\u201335.43); hospital stay\u2009&gt;\u200920\u2009days with male sex (OR\u2009=\u20092.107, 95%CI\u2009=\u20091.004\u20134.419) and L3\u2010PMI (OR\u2009=\u20090.996, 95%CI\u2009=\u20090.994\u20130.999); 1\u2009year mortality with L3\u2010PMI (OR\u2009=\u20090.996, 95%CI\u2009=\u20090.992\u20130.999). Patients at the lowest L3\u2010PMI receiving suboptimal grafts had longer ICU\/hospital stay and higher incidence of infections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Malnutrition and sarcopenia are associated with early post\u2010liver transplant morbidity\/mortality. Allocation indices do not include nutritional status and may jeopardize outcomes in nutritionally compromised individuals.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcsm.12095","type":"journal-article","created":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T08:31:39Z","timestamp":1454315499000},"page":"113-121","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":269,"title":["Malnutrition and sarcopenia predict post\u2010liver transplantation outcomes independently of the Model for End\u2010stage Liver Disease score"],"prefix":"10.1002","volume":"8","author":[{"given":"Maria","family":"Kalafateli","sequence":"first","affiliation":[{"name":"UCL Institute for Liver and Digestive Health Royal Free Hospital and UCL  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Mantzoukis","sequence":"additional","affiliation":[{"name":"UCL Institute for Liver and Digestive Health Royal Free 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