{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T11:55:42Z","timestamp":1790596542519,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,3,6]],"date-time":"2019-03-06T00:00:00Z","timestamp":1551830400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Colciencias y Ministerio de Salud y la Protecci\u00f3n Social de Colombia"},{"name":"Mikel Izquierdo is funded by ISCIII and Fondos FEDER","award":["PI17\/01814"],"award-info":[{"award-number":["PI17\/01814"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The purposes of this study were three\u2010fold: (i) to describe handgrip strength in older individuals aged \u226560\u00a0years in Colombia; (ii) to identify sex\u2010specific and age\u2010specific muscle weakness cut\u2010off points in older adults; and (iii) to determine the odds of adverse events for each of the intrinsic capacity domains for individuals with handgrip strength greater than the muscle weakness cut\u2010off points, as compared with their weaker counterparts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional study was conducted in Colombia, among 5237 older adults aged \u226560\u00a0years old (58.5% women, 70.5\u00a0\u00b1\u00a07.8\u00a0years), according to \u2018SABE Survey 2015\u2019. Handgrip strength data were obtained with a Takei dynamometer. Sociodemographic variables, five domains of intrinsic capacity (i.e. locomotion, vitality, cognition, psychological, and sensory), and medical conditions were assessed and analyzed. Adjustments variables were age, ethnicity, socio\u2010economic status, urbanicity, body mass index, smoking status, alcohol intake, drug use, physical activity, and co\u2010morbid chronic diseases. Sex\u2010stratified analyses were conducted with logistic regression models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Handgrip strength was greater among men than among women (26.7\u00a0\u00b1\u00a08.5 vs. 16.7\u00a0\u00b1\u00a05.7\u00a0kg, respectively,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) at all ages. Weak handgrip strength cut\u2010off points ranged from 17.4 to 8.6 and from 10.1 to 4.9 in men and women, respectively. Overall, participants with optimal handgrip strength had better intrinsic capacity [in men, odds ratio (OR)\u00a0=\u00a00.62, 95% confidence interval (CI) 0.53 to 0.71;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001; and in women, OR\u00a0=\u00a00.79, 95% CI 0.68 to 0.92;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.002] than their weaker counterparts. Also, men with optimal handgrip strength had a lower risk of hospitalization (OR\u00a0=\u00a00.47, 95% CI 0.29 to 0.78;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.004) than their weaker counterparts.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study is the first to describe handgrip strength values and cut\u2010off points for muscle weakness among a nationally representative sample of Colombian older adults by age and sex. After categorizing older adults as weak or not weak based on the handgrip cut\u2010off points, non\u2010weakness was associated with a decreased odds of intrinsic capacity impairments. These cut\u2010off points may be good candidates for clinical assessment of risks to physical and mental health in older Colombian adults.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcsm.12373","type":"journal-article","created":{"date-parts":[[2019,3,7]],"date-time":"2019-03-07T01:45:26Z","timestamp":1551923126000},"page":"278-286","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":115,"title":["Reference values for handgrip strength and their association with intrinsic capacity domains among older adults"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3075-6960","authenticated-orcid":false,"given":"Robinson","family":"Ram\u00edrez\u2010V\u00e9lez","sequence":"first","affiliation":[{"name":"Centro de Estudios en Medici\u00f3n de la Actividad F\u00edsica (CEMA), Escuela de Medicina y Ciencias de la Salud Universidad del Rosario  Bogot\u00e1, D.C. Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0646-2316","authenticated-orcid":false,"given":"Jorge Enrique","family":"Correa\u2010Bautista","sequence":"additional","affiliation":[{"name":"Centro de Estudios en Medici\u00f3n de la Actividad F\u00edsica (CEMA), Escuela de Medicina y Ciencias de la Salud Universidad del Rosario  Bogot\u00e1, D.C. Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1397-7182","authenticated-orcid":false,"given":"Antonio","family":"Garc\u00eda\u2010Hermoso","sequence":"additional","affiliation":[{"name":"Laboratorio de Ciencias de la Actividad F\u00edsica, el Deporte y la Salud Universidad de Santiago de Chile, USACH  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5680-7880","authenticated-orcid":false,"given":"Carlos Alberto","family":"Cano","sequence":"additional","affiliation":[{"name":"Instituto de Envejecimiento, Semillero de Neurociencias y Envejecimiento, Facultad de Medicina Pontificia Universidad Javeriana, Hospital Universitario San Ignacio  Bogot\u00e1 Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1506-4272","authenticated-orcid":false,"given":"Mikel","family":"Izquierdo","sequence":"additional","affiliation":[{"name":"Centro de Estudios en Medici\u00f3n de la Actividad F\u00edsica (CEMA), Escuela de Medicina y Ciencias de la Salud Universidad del Rosario  Bogot\u00e1, D.C. Colombia"},{"name":"Department of Health Sciences, Navarrabiomed, CIBER of Frailty and Healthy Aging (CIBERFES), Instituto de Salud Carlos III, Pamplona Public University of Navarre  Navarre Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/7910205"},{"key":"e_1_2_8_3_1","volume-title":"World Report on Ageing and Health","author":"World Health 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