{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T07:17:14Z","timestamp":1793863034930,"version":"4.6.1"},"reference-count":57,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T00:00:00Z","timestamp":1580256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012002","name":"Descente and Ishimoto Memorial Foundation for the Promotion of Sports Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2020,2]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>In longevity societies, one of the most serious social issues is sarcopenia and\/or frailty. Preventing them is important for maintaining independence and quality of life in the older population. This study investigated the effect of a self\u2010monitoring comprehensive geriatric intervention programme (CGIP) on physical function and muscle size in community\u2010dwelling older adults. We compared the effects of a CGIP using weekly class\u2010styled (CS) sessions and a home\u2010based (HB) programme.<\/jats:p><\/jats:sec>Methods<\/jats:title>The 526 participants were randomized into one of two groups (CS 251, HB 275) based on their residential districts. We conducted a 12 week CGIP, which consisted of low\u2010load resistance exercise, physical activity increments, oral function improvements, and a nutritional guide. All participants were encouraged to attend two 90 min lectures that included instructions on the CGIP. They were provided with exercise materials (triaxial\u2010accelerometers\/pedometers, ankle weights, and elastic bands) and diary logs. The CS group attended 90 min weekly sessions and independently executed the programme on other days, whereas the HB group only received instructions on how to execute the programme. Physical functions, such as knee extension strength (KES), normal and maximum walking speed, the timed up\u2010and\u2010go test, and anterior thigh muscle thickness (MT), were measured and analysed using intention\u2010to\u2010treat analysis before and after the 12 week intervention.<\/jats:p><\/jats:sec>Results<\/jats:title>Of the 526 participants identified, 517 (CS 243 age 74.0 \u00b1 5.4 women 57.2%, HB 274 age 74.0 \u00b1 5.6 women 58.8%) were enrolled. Nine (CS 8, HB 1) were excluded from the analysis because they did not participate in the pre\u2010intervention measurements. Both interventions significantly improved KES (CS 18.5%, HB 10.6%), normal walking speed (CS 3.7%, HB 2.8%), and MT (CS 3.2%, HB 3.5%). Greater improvement of KES was observed in the CS group (P<\/jats:italic> = 0.003). Maximum walking speed (CS 4.7%, HB 1.8%; P<\/jats:italic> = 0.001) and timed up\u2010and\u2010go (CS \u22124.7%, HB \u22120.2%; P<\/jats:italic> < 0.001) significantly improved in the CS group only.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The intervention was effective in preventing sarcopenia and\/or frailty. Most physical functions and MT improved after both interventions. The HB intervention is cost\u2010effective and may help prevent sarcopenia and\/or frailty in the large older population.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcsm.12504","type":"journal-article","created":{"date-parts":[[2020,1,30]],"date-time":"2020-01-30T05:38:04Z","timestamp":1580362684000},"page":"26-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Comprehensive geriatric intervention in community\u2010dwelling older adults: a cluster\u2010randomized controlled trial"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3970-1202","authenticated-orcid":false,"given":"Yuya","family":"Watanabe","sequence":"first","affiliation":[{"name":"Faculty of Health and Sports Science Doshisha University Kyoto Japan"},{"name":"Laboratory of Applied Health Sciences Kyoto Prefectural University of Medicine Kyoto Japan"},{"name":"Department of Health and Sports Sciences Kyoto Gakuen University Kameoka Japan"},{"name":"Section of Healthy Longevity Research National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4284-6317","authenticated-orcid":false,"given":"Yosuke","family":"Yamada","sequence":"additional","affiliation":[{"name":"Laboratory of Applied Health Sciences Kyoto Prefectural University of Medicine Kyoto Japan"},{"name":"Section of Healthy Longevity Research National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2304-6872","authenticated-orcid":false,"given":"Tsukasa","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Laboratory of Applied Health Sciences Kyoto Prefectural University of Medicine Kyoto Japan"},{"name":"Section of Healthy Longevity Research National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition Tokyo Japan"},{"name":"Senior Citizen's Welfare Section Kameoka City Government Kameoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichi","family":"Yokoyama","sequence":"additional","affiliation":[{"name":"Non\u2010profit Organization Genki\u2010up AGE Project Kameoka Japan"},{"name":"Department of Business Administration Kyoto Gakuen University Kameoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motoko","family":"Miyake","sequence":"additional","affiliation":[{"name":"Department of Health and Sports Sciences Kyoto Gakuen University Kameoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emi","family":"Yamagata","sequence":"additional","affiliation":[{"name":"Faculty of Nursing Doshisha Women's College of Liberal Arts Kyotanabe 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