{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T13:16:50Z","timestamp":1782739010257,"version":"3.54.5"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,2,4]],"date-time":"2021-02-04T00:00:00Z","timestamp":1612396800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Regular stair climbing has the potential to lower the risk of premature death, but current evidence is scarce. We aimed to examine whether daily stair climbing is associated with lower risk of all\u2010cause, cancer, and cardiovascular disease (CVD) mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using the UK Biobank cohort, we extracted information of self\u2010reported daily flights of stairs climbed at home, categorized as none, 1 to 5, 6 to 10, 11 to 15, and \u226516 flights per day. Associations between flights of stair climbed per day and mortality were examined as hazard ratios (HRs) from Cox proportional hazards models adjusted for demographic, clinical, and behavioural covariates including time spent in other physical activities. We calculated the restricted mean survival time as an absolute measure of association. The risk of residual confounding was examined using propensity score matching and by using lung cancer as negative control outcome. Participants were followed from baseline (2006\u20132010) through 31 March 2020.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 280\u00a0423 participants (median follow\u2010up 11.1\u00a0years, during which 9445 deaths occurred) were included. Compared with not climbing any stairs, climbing more than five flights of stairs at home per day was associated with lower risk of premature mortality. The lowest risk was found for those climbing 6\u201310 flights per day: 0.91; 95% confidence interval (CI): 0.85, 0.98, translated to approximately 44 to 55\u00a0days of additional survival. A similar pattern was found after applying propensity score matching and for cancer mortality (6\u201310 flights per day HR: 0.88; 95% CI: 0.80, 0.97), but not for CVD mortality (6\u201310 flights per day HR: 1.08; 95% CI: 0.91, 1.29). The association between stair climbing and lung cancer was similar to that of all\u2010cause mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Climbing more than five flights of stairs at home per day was associated with a lower risk of all\u2010cause and cancer mortality, but not CVD mortality, compared with those who did not take the stairs. The magnitude of the association was small and appeared susceptible to residual confounding. It is unlikely that at\u2010home stair climbing is sufficient physical activity stimuli to lower the risk of premature mortality.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcsm.12679","type":"journal-article","created":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T02:13:17Z","timestamp":1612750397000},"page":"298-307","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Stair climbing and mortality: a prospective cohort study from the UK Biobank"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7457-3475","authenticated-orcid":false,"given":"Miguel A.","family":"Sanchez\u2010Lastra","sequence":"first","affiliation":[{"name":"Department of Special Didactics, Faculty of Education and Sport Sciences University of Vigo  Pontevedra Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding","family":"Ding","sequence":"additional","affiliation":[{"name":"Prevention Research Collaboration, Sydney School of Public Health The University of Sydney  Camperdown New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knut\u2010Eirik","family":"Dalene","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine Norwegian School of Sports Sciences  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Borja","family":"del Pozo Cruz","sequence":"additional","affiliation":[{"name":"Motivation and Behaviour Research Program, Institute for Positive Psychology and Education, Faculty of Health Sciences Australian Catholic University  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulf","family":"Ekelund","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine Norwegian School of Sports Sciences  Oslo Norway"},{"name":"Department of Chronic Diseases and Ageing Norwegian Institute of Public Health  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9186-7077","authenticated-orcid":false,"given":"Jakob","family":"Tarp","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine Norwegian School of Sports Sciences  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,4]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"World Health Organization (WHO).Global action plan on physical activity 2018\u20132030: more active people for a healthier world.WHO2019http:\/\/www.who.int\/ncds\/prevention\/physical-activity\/global-action-plan-2018-2030\/en\/. 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