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This investigation aimed to assess the relationship between relative STS power and age and to provide normative data, cut\u2010off points, and minimal clinically important differences (MCID) for STS power measures in older women and men.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 9320 older adults (6161 women and 3159 men) aged 60\u2013103\u00a0years and 586 young and middle\u2010aged adults (318 women and 268 men) aged 20\u201360\u00a0years were included in this cross\u2010sectional study. Relative (normalized to body mass), allometric (normalized to height squared), and specific (normalized to legs muscle mass) muscle power values were assessed by the 30\u00a0s STS power test. Body composition was evaluated by dual energy X\u2010ray absorptiometry and bioelectrical impedance analysis, and legs skeletal muscle index (SMI; normalized to height squared) was calculated. Habitual and maximal gait speed, timed up\u2010and\u2010go test, and 6\u00a0min walking distance were collected as physical performance measures, and participants were classified into two groups: well\u2010functioning and mobility\u2010limited older adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Relative STS power was found to decrease between 30\u201350\u00a0years (\u22120.05\u00a0W\u00b7kg<jats:sup>\u22121<\/jats:sup>\u00b7year<jats:sup>\u22121<\/jats:sup>; <jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05), 50\u201380\u00a0years (\u22120.10 to \u22120.13\u00a0W\u00b7kg<jats:sup>\u22121<\/jats:sup>\u00b7year<jats:sup>\u22121<\/jats:sup>; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), and above 80\u00a0years (\u22120.07 to \u22120.08\u00a0W\u00b7kg<jats:sup>\u22121<\/jats:sup>\u00b7year<jats:sup>\u22121<\/jats:sup>; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). A total of 1129 older women (18%) and 510 older men (16%) presented mobility limitations. Mobility\u2010limited older adults were older and exhibited lower relative, allometric, and specific power; higher body mass index (BMI) and legs SMI (both only in women); and lower legs SMI (only in men) than their well\u2010functioning counterparts (all <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). Normative data and cut\u2010off points for relative, allometric, and specific STS power and for BMI and legs SMI were reported. Low relative STS power occurred below 2.1\u00a0W\u00b7kg<jats:sup>\u22121<\/jats:sup> in women (area under the curve, AUC, [95% confidence interval, CI]\u00a0=\u00a00.85 [0.84\u20130.87]) and below 2.6\u00a0W\u00b7kg<jats:sup>\u22121<\/jats:sup> in men (AUC [95% CI]\u00a0=\u00a00.89 [0.87\u20130.91]). The age\u2010adjusted odds ratios [95% CI] for mobility limitations in older women and men with low relative STS power were 10.6 [9.0\u201312.6] and 14.1 [10.9\u201318.2], respectively. MCID values for relative STS power were 0.33\u00a0W\u00b7kg<jats:sup>\u22121<\/jats:sup> in women and 0.42\u00a0W\u00b7kg<jats:sup>\u22121<\/jats:sup> in men.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Relative STS power decreased significantly after the age of 50\u00a0years and was negatively and strongly associated with mobility limitations. Our study provides normative data, functionally relevant cut\u2010off points, and MCID values for STS power for their use in daily clinical practice.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcsm.12737","type":"journal-article","created":{"date-parts":[[2021,7,3]],"date-time":"2021-07-03T08:42:39Z","timestamp":1625301759000},"page":"921-932","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":94,"title":["Relative sit\u2010to\u2010stand power: aging trajectories, functionally relevant cut\u2010off points, and normative data in a large European cohort"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1090-5482","authenticated-orcid":false,"given":"Julian","family":"Alcazar","sequence":"first","affiliation":[{"name":"GENUD Toledo Research Group Universidad de Castilla\u2010La Mancha  Toledo Spain"},{"name":"CIBER of Frailty and Healthy Aging (CIBERFES)  Madrid Spain"},{"name":"Geriatric Research Unit, Geriatric Department Bispebjerg\u2010Frederiksberg University Hospital  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4502-9275","authenticated-orcid":false,"given":"Luis M.","family":"Alegre","sequence":"additional","affiliation":[{"name":"GENUD Toledo Research Group Universidad de Castilla\u2010La Mancha  Toledo Spain"},{"name":"CIBER of Frailty and Healthy Aging (CIBERFES)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelien","family":"Van Roie","sequence":"additional","affiliation":[{"name":"Department of Movement Sciences, Physical Activity, Sports and Health Research Group KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o P.","family":"Magalh\u00e3es","sequence":"additional","affiliation":[{"name":"Exercise and Health Laboratory, CIPER, Facultade de Motricidade Humana Universidade de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara R.","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Geriatric Division Amager and Hvidovre Hospital, Glostrup  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela","family":"Gonz\u00e1lez\u2010Gross","sequence":"additional","affiliation":[{"name":"ImFine Research Group, Departamento de Salud y Rendimiento Humano, Facultad de Ciencias de la Actividad F\u00edsica y del Deporte Universidad Polit\u00e9cnica de Madrid  Madrid Spain"},{"name":"CIBER of Pathophysiology of Obesity and Nutrition (CIBEROBN)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro B.","family":"J\u00fadice","sequence":"additional","affiliation":[{"name":"Exercise and Health Laboratory, CIPER, Facultade de Motricidade Humana Universidade de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose A.","family":"Casaj\u00fas","sequence":"additional","affiliation":[{"name":"CIBER of Pathophysiology of Obesity and Nutrition (CIBEROBN)  Madrid Spain"},{"name":"Growth, Exercise, Nutrition, and Development Research Group University of Zaragoza  Zaragoza Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Delecluse","sequence":"additional","affiliation":[{"name":"Department of Movement Sciences, Physical Activity, Sports and Health Research Group KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis B.","family":"Sardinha","sequence":"additional","affiliation":[{"name":"Exercise and Health Laboratory, CIPER, Facultade de Motricidade Humana Universidade de Lisboa  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Suetta","sequence":"additional","affiliation":[{"name":"Geriatric Research Unit, Geriatric Department Bispebjerg\u2010Frederiksberg University Hospital  Copenhagen Denmark"},{"name":"Department of Clinical Physiology, Nuclear Medicine &amp; 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