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Yet, whether individuals with weaker muscle strength are more at risk for hospitalization due to severe COVID\u201019 is still unclear. The objective of this study was to investigate the independent association between muscle strength and COVID\u201019 hospitalization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data from adults 50\u00a0years of age or older were analysed using logistic models adjusted for several chronic conditions, body\u2010mass index, age, and sex. Hand\u2010grip strength was repeatedly measured between 2004 and 2017 using a handheld dynamometer. COVID\u201019 hospitalization during the lockdown was self\u2010reported in summer 2020 and was used as an indicator of COVID\u201019 severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The study was based on the Survey of Health, Ageing and Retirement in Europe (SHARE) and included 3600 older adults (68.8\u00a0\u00b1\u00a08.8\u00a0years, 2044 female), among whom 316 were tested positive for the severe acute respiratory syndrome coronavirus 2 (8.8%), and 83 (2.3%) were hospitalized due to COVID\u201019. Results showed that higher grip strength was associated with a lower risk of COVID\u201019 hospitalization [adjusted odds ratio (OR) per increase of 1 standard deviation in grip strength\u00a0=\u00a00.64, 95% confidence interval (95% CI)\u00a0=\u00a00.45\u20130.87,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.015]. Results also showed that age (OR for a 10\u00a0\u2010year period\u00a0=\u00a01.70, 95% CI\u00a0=\u00a01.32\u20132.20,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) and obesity (OR\u00a0=\u00a02.01, 95% CI\u00a0=\u00a01.00\u20133.69,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.025) were associated with higher risk of COVID\u201019 hospitalization. Sensitivity analyses using different measurements of grip strength as well as robustness analyses based on rare\u2010events logistic regression and a different sample of participants (i.e. COVID\u201019 patients) were consistent with the main results.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Muscle strength is an independent risk factor for COVID\u201019 severity in adults 50\u00a0years of age or older.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcsm.12738","type":"journal-article","created":{"date-parts":[[2021,8,7]],"date-time":"2021-08-07T03:39:13Z","timestamp":1628307553000},"page":"1136-1143","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Muscle strength is associated with COVID\u201019 hospitalization in adults 50 years of age or older"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6236-4673","authenticated-orcid":false,"given":"Boris","family":"Cheval","sequence":"first","affiliation":[{"name":"Swiss Center for Affective Sciences University of Geneva  Geneva Switzerland"},{"name":"Laboratory for the Study of Emotion Elicitation and Expression (E3Lab), Department of Psychology University of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7669-2478","authenticated-orcid":false,"given":"Stefan","family":"Sieber","sequence":"additional","affiliation":[{"name":"Swiss NCCR \u2018LIVES\u2014Overcoming Vulnerability: Life Course Perspectives\u2019 University of Geneva  Geneva Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7199-0599","authenticated-orcid":false,"given":"Silvio","family":"Maltagliati","sequence":"additional","affiliation":[{"name":"SENS Univ. Grenoble Alpes  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8081-4423","authenticated-orcid":false,"given":"Gr\u00e9goire P.","family":"Millet","sequence":"additional","affiliation":[{"name":"Institute of Sport Sciences University of Lausanne  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6740-6860","authenticated-orcid":false,"given":"Tom\u00e1\u0161","family":"Form\u00e1nek","sequence":"additional","affiliation":[{"name":"Department of Public Mental Health National Institute of Mental Health  Klecany Czech Republic"},{"name":"EpiCentre, Department of Psychiatry University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1806-354X","authenticated-orcid":false,"given":"A\u00efna","family":"Chalabaev","sequence":"additional","affiliation":[{"name":"SENS Univ. 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