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It has been indicated as a potential negative factor in the survival of patients with malignant tumours. The aim of this systematic review and meta\u2010analysis was to evaluate the associations between sarcopenia and survival outcomes or postoperative complications in patients with oesophageal cancer (EC). Web of Science, Embase, Medline, and Cochrane Library databases were searched until 10 May 2022, using keywords: sarcopenia, oesophageal cancer, and prognosis. Studies investigating the prognostic value of sarcopenia on EC survival were included. Forest plots and summary effect models were used to show the result of this meta\u2010analysis. The quality of included studies was evaluated with the Newcastle\u2010Ottawa Scale (NOS). A total of 1436 studies were identified from the initial search of four databases, and 41 studies were included for the final quantitative analysis. This meta\u2010analysis revealed a significant association between sarcopenia and overall survival (OS) [hazard ratios (HR):1.68, 95% confidence interval (CI):1.54\u20131.83,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.004,\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a041.7%] or disease\u2010free survival (DFS) 1.97 (HR: 1.97, 95% CI: 1.44\u20132.69,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.007,\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a061.9%) of EC patients. Subgroup analysis showed that sarcopenia remained a consistent negative predictor of survival when stratified by different treatment methods, populations, or sarcopenia measurements. Sarcopenia was also a risk factor for postoperative complications with a pooled odds ratio of 1.47 (95% CI: 1.21\u20131.77,\n                    <jats:italic>P<\/jats:italic>\n                    \u00a0=\u00a00.094,\n                    <jats:italic>I<\/jats:italic>\n                    <jats:sup>2<\/jats:sup>\n                    \u00a0=\u00a032.7%). The NOS scores of all included studies were \u22656, and the quality of the evidence was relatively high. The results from the study suggested that sarcopenia was significantly associated with both survival outcomes and postoperative complications in EC patients. Sarcopenia should be appropriately diagnosed and treated for improving short\u2010term and long\u2010term outcomes of patients with EC.\n                  <\/jats:p>","DOI":"10.1002\/jcsm.13126","type":"journal-article","created":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T01:54:23Z","timestamp":1669168463000},"page":"3-16","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":121,"title":["The prognostic value of sarcopenia in oesophageal cancer: A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"14","author":[{"given":"Pinhao","family":"Fang","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Med+X Center for Informatics, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianfeng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Med+X Center for Informatics, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Med+X Center for Informatics, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yushang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Med+X Center for Informatics, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyuan","family":"Luan","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Med+X Center for Informatics, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwen","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Med+X Center for Informatics, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaokun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Med+X Center for Informatics, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanlu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Med+X Center for Informatics, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qixin","family":"Shang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Med+X Center for Informatics, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxi","family":"Zeng","sequence":"additional","affiliation":[{"name":"West China Biomedical Big Data Center, Med+X Center for Informatics, West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9720-1965","authenticated-orcid":false,"given":"Yong","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Med+X Center for Informatics, West China Hospital Sichuan University  Chengdu 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