{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T22:25:16Z","timestamp":1792621516241,"version":"4.5.0"},"reference-count":108,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2020YFC2005601"],"award-info":[{"award-number":["2020YFC2005601"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970715"],"award-info":[{"award-number":["81970715"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Sarcopenia is an age\u2010related disease and is often accompanied by other diseases. Now, many studies have shown that cardiovascular diseases (CVDs) may raise the incidence rate of sarcopenia. Therefore, the purpose of this study was to conduct a systematic review and meta\u2010analysis to investigate the prevalence of sarcopenia in patients with CVDs compared with the general population, defined as relatively healthy non\u2010hospitalized subjects. The databases of PubMed, Embase, Medline and Web of Science were searched for eligible studies published up to 12 November 2022. Two assessment tools were used to evaluate study quality and the risk of bias. Statistical analysis was conducted using STATA 14.0 and R Version 4.1.2. Thirty\u2010eight out of the 89\u00a0629 articles retrieved were included in our review. The prevalence of sarcopenia ranged from 10.1% to 68.9% in patients with CVDs, and the pooled prevalence was 35% (95% confidence interval [95% CI]: 28\u201342%). The pooled prevalence of sarcopenia was 32% (95% CI: 23\u201341%) in patients with chronic heart failure (CHF), 61% (95% CI: 49\u201372%) in patients with acute decompensated heart failure (ADHF), 43% (95% CI: 2\u201385%) in patients with coronary artery disease, 30% (95% CI: 25\u201335%) in patients with cardiac arrhythmia (CA), 35% (95% CI: 10\u201359%) in patients with congenital heart disease and 12% (95% CI: 7\u201317%) in patients with unclassed CVDs. However, in the general population, the prevalence of sarcopenia varied from 2.9% to 28.6% and the pooled prevalence was 13% (95% CI: 9\u201317%), suggesting that the prevalence of sarcopenia in patients with CVDs was about twice compared with the general population. The prevalence of sarcopenia was significantly higher only in patients with ADHF, CHF and CA compared with the general population. There is a positive correlation between CVDs and sarcopenia. The prevalence of sarcopenia is higher in patients with CVDs than that in the general population. With global aging, sarcopenia has brought a heavy burden to individuals and society. Therefore, it is important to identify the populations with high\u2010risk or probable sarcopenia in order to do an early intervention, such as exercise, to counteract or slow down the progress of sarcopenia.<\/jats:p>","DOI":"10.1002\/jcsm.13221","type":"journal-article","created":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T05:41:09Z","timestamp":1680327669000},"page":"1183-1198","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":214,"title":["Sarcopenia and cardiovascular diseases: A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"14","author":[{"given":"Xinrong","family":"Zuo","sequence":"first","affiliation":[{"name":"Department of Anesthesiology The Affiliated Hospital of Southwest Medical University  Luzhou Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuehong","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Laboratory of Mitochondria and Metabolism, National Clinical Research Center for Geriatrics West China Hospital of Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuo","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Laboratory of Mitochondria and Metabolism, National Clinical Research Center for Geriatrics West China Hospital of Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Laboratory of Mitochondria and Metabolism, National Clinical Research Center for Geriatrics West China Hospital of Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minming","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Laboratory of Mitochondria and Metabolism, National Clinical Research Center for Geriatrics West China Hospital of Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Laboratory of Mitochondria and Metabolism, National Clinical Research Center for Geriatrics West China Hospital of Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7988-3090","authenticated-orcid":false,"given":"Tao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology The Affiliated Hospital of Southwest Medical University  Luzhou Sichuan China"},{"name":"Department of Anesthesiology, Laboratory of Mitochondria and Metabolism, National Clinical Research Center for Geriatrics West China Hospital of Sichuan University  Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/127.5.990S"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31138-9"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2016.06.001"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.11.010"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32008-2"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs381"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.07.135"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-020-01561-9"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.31744\/einstein_journal\/2019AO4632"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2019.06.011"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.015639"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.656181"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12652"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glw343"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2020.06.003"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.33000"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2022.06.041"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-021-01626-4"},{"key":"e_1_2_9_20_1","unstructured":"Quality assessment tool for observational cohort and cross\u2010sectional studies.https:\/\/www.nhlbi.nih.gov\/health\u2010topics\/study\u2010quality\u2010assessment\u2010tools"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2011.11.014"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjpc\/zwaa117"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2020.12.033"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2020.03.004"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2019.07.002"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.12545"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2019.01.003"},{"key":"e_1_2_9_28_1","first-page":"979","article-title":"Related factors of sarcopenia in hospitalized elderly patients with coronary heart disease","volume":"47","author":"Ning Z","year":"2019","journal-title":"Chin J Cardiol"},{"key":"e_1_2_9_29_1","first-page":"739","article-title":"Sympatho\u2010vagal imbalance is associated with sarcopenia in male patients with heart failure","volume":"112","author":"Fonseca G","year":"2019","journal-title":"Arq Bras Cardiol"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.17-057"},{"key":"e_1_2_9_31_1","first-page":"212","article-title":"Sarcopenia and long\u2010term prognosis of patients with chronic heart failure in patients aged 70\u00a0years and over","volume":"57","author":"Hu GF","year":"2018","journal-title":"Zhonghua Nei Ke Za Zhi"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1304"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12193"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2016.09.006"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.04.128"},{"key":"e_1_2_9_36_1","first-page":"116","article-title":"Sarcopenia in heart failure with reduced ejection fraction","volume":"9","author":"Canteri AL","year":"2019","journal-title":"Am J Cardiovasc Dis"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2013.11.025"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2019.12.012"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8223(00)00021-3"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwh058"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1067\/mlc.2001.113504"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afq034"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afy169"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009520"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2011.04.014"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12268"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2003.51534.x"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glu010"},{"key":"e_1_2_9_49_1","first-page":"1851","article-title":"Age\u2010associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia","volume":"2003","author":"Lauretani F","year":"1985","journal-title":"J Appl Physiol"},{"key":"e_1_2_9_50_1","first-page":"3","article-title":"Grip strength reference values for Canadians aged 6 to 79: Canadian Health Measures Survey, 2007 to 2013","volume":"27","author":"Wong SL","year":"2016","journal-title":"Health Rep"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glu013"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-011-0365-1"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.12197"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-009-1059-y"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2021.12.015"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2016.11.005"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00129.2003"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.047381"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2021.10.013"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2022.155348"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.85.5.1751"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.eurheartj.a015386"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.81.2.518"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glp097"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2006-0251"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01736-9"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2016.03.011"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.41641"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2108013"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-016-3823-0"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs463"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.02.038"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.882068"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0085820"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.2220\/biomedres.36.383"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00141.2015"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-205007"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13029"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-022-01153-1"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afac003"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.675041"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2021.01.058"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12543"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12941"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12306"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12504"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12483"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-021-00463-6"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0951com"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2013.08.019"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0705070104"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M805078200"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1105062108"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-physiol-020518-114310"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.1097\/HCR.0b013e3182642688"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.032432"},{"key":"e_1_2_9_97_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.592"},{"key":"e_1_2_9_98_1","article-title":"Skeletal muscle mass recovery early after left ventricular assist device implantation in patients with advanced systolic heart failure","author":"Vest AR","year":"2022","journal-title":"Circ Heart Fail"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.120.317933"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-020-0363-2"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2014.83"},{"key":"e_1_2_9_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3363"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16132"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2019.05.007"},{"key":"e_1_2_9_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2021.101994"},{"key":"e_1_2_9_106_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00875.2007"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-010-1777-z"},{"key":"e_1_2_9_108_1","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2019-052592","article-title":"Sarcopenia: early prevention or overdiagnosis?","volume":"376","author":"Haase CB","year":"2022","journal-title":"BMJ"},{"key":"e_1_2_9_109_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-018-1139-9"}],"container-title":["Journal of Cachexia, Sarcopenia and Muscle"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcsm.13221","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T23:09:38Z","timestamp":1703804978000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcsm.13221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":108,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1002\/jcsm.13221"],"URL":"https:\/\/doi.org\/10.1002\/jcsm.13221","archive":["Portico"],"relation":{},"ISSN":["2190-5991","2190-6009"],"issn-type":[{"value":"2190-5991","type":"print"},{"value":"2190-6009","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"2022-06-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}