{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:35:56Z","timestamp":1791668156103,"version":"4.3.4"},"reference-count":115,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T00:00:00Z","timestamp":1715558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Significant variation exists in the outcomes used in cancer cachexia trials, including measures of body composition, which are often selected as primary or secondary endpoints. To date, there has been no review of the most commonly selected measures or their potential sensitivity to detect changes resulting from the interventions being examined. The aim of this systematic review is to assess the frequency and diversity of body composition measures that have been used in cancer cachexia trials. MEDLINE, Embase and Cochrane Library databases were systematically searched between January 1990 and June 2021. Eligible trials examined adults (\u226518\u00a0years) who had received an intervention aiming to treat or attenuate the effects of cancer cachexia for &gt;14\u00a0days. Trials were also of a prospective controlled design and included body weight or at least one anthropometric, bioelectrical or radiological endpoint pertaining to body composition, irrespective of the modality of intervention (e.g., pharmacological, nutritional, physical exercise and behavioural) or comparator. Trials with a sample size of &lt;40 patients were excluded. Data extraction used Covidence software, and reporting followed the Preferred Reporting Items for Systematic Reviews and Meta\u2010Analyses guidance. This review was prospectively registered (PROSPERO: CRD42022276710). A total of 84 clinical trials, comprising 13\u00a0016 patients, were eligible for inclusion. Non\u2010small\u2010cell lung cancer and pancreatic cancer were studied most frequently. The majority of trial interventions were pharmacological (52%) or nutritional (34%) in nature. The most frequently reported endpoints were assessments of body weight (68 trials,\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a011\u00a0561) followed by bioimpedance analysis (BIA)\u2010based estimates (23 trials,\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a03140). Sixteen trials (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a03052) included dual\u2010energy X\u2010ray absorptiometry (DEXA)\u2010based endpoints, and computed tomography (CT) body composition was included in eight trials (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a0841). Discrepancies were evident when comparing the efficacy of interventions using BIA\u2010based estimates of lean tissue mass against radiological assessment modalities. Body weight, BIA and DEXA\u2010based endpoints have been most frequently used in cancer cachexia trials. Although the optimal endpoints cannot be determined from this review, body weight, alongside measurements from radiological body composition analysis, would seem appropriate. The choice of radiological modality is likely to be dependent on the trial setting, population and intervention in question. CT and magnetic resonance imaging, which have the ability to accurately discriminate tissue types, are likely to be more sensitive and provide greater detail. Endpoints are of particular importance when aligned with the intervention's mechanism of action and\/or intended patient benefit.\n                  <\/jats:p>","DOI":"10.1002\/jcsm.13478","type":"journal-article","created":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T06:28:46Z","timestamp":1715581726000},"page":"816-852","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Body weight and composition endpoints in cancer cachexia clinical trials: Systematic Review 4 of the cachexia endpoints series"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6181-7020","authenticated-orcid":false,"given":"Leo R.","family":"Brown","sequence":"first","affiliation":[{"name":"Clinical Surgery The University of Edinburgh, Royal Infirmary of Edinburgh  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana S.","family":"Sousa","sequence":"additional","affiliation":[{"name":"Improving Palliative, Aged and Chronic Care Through Clinical Research and Translation (IMPACCT) University of Technology Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Yule","sequence":"additional","affiliation":[{"name":"Clinical Surgery The University of Edinburgh, Royal Infirmary of Edinburgh  Edinburgh UK"},{"name":"Institute of Genetics and Cancer The University of Edinburgh, Western General Hospital  Edinburgh UK"},{"name":"St Columba's Hospice Care  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vickie E.","family":"Baracos","sequence":"additional","affiliation":[{"name":"Department of Oncology University of Alberta  Edmonton Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald C.","family":"McMillan","sequence":"additional","affiliation":[{"name":"Academic Unit of Surgery University of Glasgow, Glasgow Royal Infirmary  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jann","family":"Arends","sequence":"additional","affiliation":[{"name":"Department of Medicine I, Medical Centre\u2014University of Freiburg Faculty of Medicine University of Freiburg  Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trude R.","family":"Balstad","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences Norwegian University of Science and Technology  Trondheim Norway"},{"name":"Department of Clinical Medicine, Clinical Nutrition Research Group UiT The Arctic University of Norway  Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asta","family":"Bye","sequence":"additional","affiliation":[{"name":"Department of Oncology Oslo University Hospital  Oslo Norway"},{"name":"Department of Nursing and Health Promotion, Faculty of Health Sciences Oslo Metropolitan University  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olav","family":"Dajani","sequence":"additional","affiliation":[{"name":"Department of Oncology Oslo University Hospital  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross D.","family":"Dolan","sequence":"additional","affiliation":[{"name":"Academic Unit of Surgery University of Glasgow, Glasgow Royal Infirmary  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie T.","family":"Fallon","sequence":"additional","affiliation":[{"name":"Institute of Genetics and Cancer The University of Edinburgh, Western General Hospital  Edinburgh UK"},{"name":"St Columba's Hospice Care  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Greil","sequence":"additional","affiliation":[{"name":"Department of Medicine I, Medical Centre\u2014University of Freiburg Faculty of Medicine University of Freiburg  Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne J.","family":"Hjermstad","sequence":"additional","affiliation":[{"name":"Department of Oncology Oslo University Hospital  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunnhild","family":"Jakobsen","sequence":"additional","affiliation":[{"name":"Department of Public Health and Nursing, Faculty of Medicine and Health Sciences Norwegian University of Science and Technology  Trondheim Norway"},{"name":"Cancer Clinic St. Olav's Hospital, Trondheim University Hospital  Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Maddocks","sequence":"additional","affiliation":[{"name":"Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"McDonald","sequence":"additional","affiliation":[{"name":"Institute of Genetics and Cancer The University of Edinburgh, Western General Hospital  Edinburgh UK"},{"name":"St Columba's Hospice Care  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inger O.","family":"Ottestad","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Institute of Basic Medical Sciences University of Oslo  Oslo Norway"},{"name":"The Clinical Nutrition Outpatient Clinic, Section of Clinical Nutrition, Department of Clinical Service, Division of Cancer Medicine Oslo University Hospital  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain","family":"Phillips","sequence":"additional","affiliation":[{"name":"Edinburgh Cancer Centre Western General Hospital  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Sayers","sequence":"additional","affiliation":[{"name":"Clinical Surgery The University of Edinburgh, Royal Infirmary of Edinburgh  Edinburgh UK"},{"name":"Institute of Genetics and Cancer The University of Edinburgh, Western General Hospital  Edinburgh UK"},{"name":"St Columba's Hospice Care  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie R.","family":"Simpson","sequence":"additional","affiliation":[{"name":"Department of Nursing and Health Promotion, Faculty of Health Sciences Oslo Metropolitan University  Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ola M.","family":"Vagnildhaug","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences Norwegian University of Science and Technology  Trondheim Norway"},{"name":"Department of Public Health and Nursing, Faculty of Medicine and Health Sciences Norwegian University of Science and Technology  Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tora S.","family":"Solheim","sequence":"additional","affiliation":[{"name":"Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences Norwegian University of Science and Technology  Trondheim Norway"},{"name":"Department of Public Health and Nursing, Faculty of Medicine and Health Sciences Norwegian University of Science and Technology  Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry J.A.","family":"Laird","sequence":"additional","affiliation":[{"name":"Institute of Genetics and Cancer The University of Edinburgh, Western General Hospital  Edinburgh UK"},{"name":"St Columba's Hospice Care  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J.E.","family":"Skipworth","sequence":"additional","affiliation":[{"name":"Clinical Surgery The University of Edinburgh, Royal Infirmary of Edinburgh  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Cancer Cachexia Endpoints Working Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70218-7"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.105"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1139\/H08-075"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcibr1106880"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afy169"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-68797-3"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2700"},{"key":"e_1_2_7_9_1","volume-title":"A systematic literature review examining endpoints for cancer cachexia trials","author":"Solheim T","year":"2022"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13321"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.52.6.377"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)00558-6"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19900615)65:12<2657::AID-CNCR2820651210>3.0.CO;2-S"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/82.13.1127"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-199210000-00008"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1993.202"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1993.11.4.762"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1993.11.10.2043"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1995.13.11.2856"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1996.297"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0959-8049(96)00136-0"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1996.14.4.1077"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008291825695"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(97)01921-X"},{"key":"e_1_2_7_25_1","first-page":"5374","article-title":"Protection of metabolic and exercise capacity in unselected weight\u2010losing cancer patients following treatment with recombinant erythropoietin: a randomized prospective study","volume":"58","author":"Daneryd P","year":"1998","journal-title":"Cancer Res"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(98)00219-6"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-199808000-00006"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1999.17.10.3299"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6690077"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(98)00398-0"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.20.2.567"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1207\/S15327914NC421_7"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089160208800406"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.01.101"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.10.1479"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6601962"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20160"},{"key":"e_1_2_7_38_1","first-page":"320","article-title":"Nutritional intervention improves the caloric and proteic ingestion of head and neck cancer patients under radiotherapy","volume":"20","author":"Gon\u00e7alves Dias MC","year":"2005","journal-title":"Nutr Hosp"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.047563"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.04.5724"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-008-0403-7"},{"key":"e_1_2_7_42_1","first-page":"18","article-title":"A multicenter, phase II study of infliximab plus gemcitabine in pancreatic cancer cachexia","volume":"6","author":"Wiedenmann B","year":"2008","journal-title":"J Support Oncol"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/CAD.0b013e32832d4f22"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2009-0153"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-009-0739-7"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-277X.2011.01189.x"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2891-11-52"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2011.12.435"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2011.10.005"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21700"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1159\/000346446"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.43.6766"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70055-X"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1177\/030089161309900218"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2013.10.019"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0108687"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-14-382"},{"key":"e_1_2_7_58_1","first-page":"5","article-title":"Dietetic and psychological mindfulness workshops for the management of cachectic cancer patients. A randomized study","volume":"3","author":"Focan C","year":"2015","journal-title":"Anticancer Res"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)71154-4"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29863"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1177\/1534735416651968"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.4103\/2277-9175.179182"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12126"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-016-3144-z"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2016.09.001"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx192"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx232"},{"key":"e_1_2_7_68_1","doi-asserted-by":"publisher","DOI":"10.1080\/01635581.2017.1283421"},{"key":"e_1_2_7_69_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30901"},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12201"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-017-0495-5"},{"key":"e_1_2_7_72_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu9101108"},{"key":"e_1_2_7_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12331"},{"key":"e_1_2_7_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.31128"},{"key":"e_1_2_7_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-018-4047-y"},{"key":"e_1_2_7_76_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-018-4790-y"},{"key":"e_1_2_7_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2017.05.027"},{"key":"e_1_2_7_78_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-1482.188436"},{"key":"e_1_2_7_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2019.06.003"},{"key":"e_1_2_7_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2018.09.027"},{"key":"e_1_2_7_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2517"},{"key":"e_1_2_7_82_1","first-page":"439","article-title":"Safety and tolerability of targeted medical nutrition for cachexia in non\u2010small\u2010cell lung cancer: a randomized, double\u2010blind, controlled pilot trial","volume":"72","author":"Laviano A","year":"2020","journal-title":"Controlled Pilot Trial Nutr Cancer"},{"key":"e_1_2_7_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2017.12.011"},{"key":"e_1_2_7_84_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-018-4478-5"},{"key":"e_1_2_7_85_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0000000000001221"},{"key":"e_1_2_7_86_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2019-0856"},{"key":"e_1_2_7_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2020.105025"},{"key":"e_1_2_7_88_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269215520941912"},{"key":"e_1_2_7_89_1","doi-asserted-by":"publisher","DOI":"10.3233\/MNM-200424"},{"key":"e_1_2_7_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2019.110558"},{"key":"e_1_2_7_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2020.04.008"},{"key":"e_1_2_7_92_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-82120-8"},{"key":"e_1_2_7_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2021.05.017"},{"key":"e_1_2_7_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2021.11.011"},{"key":"e_1_2_7_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2020.05.050"},{"key":"e_1_2_7_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2022.111704"},{"key":"e_1_2_7_97_1","first-page":"321","article-title":"Definition and diagnostic criteria for sarcopenic obesity: ESPEN and EASO consensus statement","author":"Donini LM","year":"2022","journal-title":"Clin Nutr"},{"key":"e_1_2_7_98_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.56.1894"},{"key":"e_1_2_7_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2018.10.008"},{"key":"e_1_2_7_100_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-015-0510-9"},{"key":"e_1_2_7_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnesp.2021.04.021"},{"key":"e_1_2_7_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12268"},{"key":"e_1_2_7_103_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/80083156"},{"key":"e_1_2_7_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2019.102839"},{"key":"e_1_2_7_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2015.12.030"},{"key":"e_1_2_7_106_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k4931"},{"key":"e_1_2_7_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2005.11.007"},{"key":"e_1_2_7_108_1","first-page":"75","article-title":"Reliability of multifrequency bioelectrical impedance analysis to quantify body composition in patients after musculoskeletal trauma","volume":"42","author":"Koch B","year":"2022","journal-title":"Iowa Orthop J"},{"key":"e_1_2_7_109_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12573"},{"key":"e_1_2_7_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2022.03.016"},{"key":"e_1_2_7_111_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13550-021-00834-2"},{"key":"e_1_2_7_112_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13080"},{"key":"e_1_2_7_113_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPC.0000000000000381"},{"key":"e_1_2_7_114_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2032183"},{"key":"e_1_2_7_115_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12383"},{"key":"e_1_2_7_116_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12083"}],"container-title":["Journal of Cachexia, Sarcopenia and Muscle"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcsm.13478","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T00:21:02Z","timestamp":1717978862000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcsm.13478"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,13]]},"references-count":115,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1002\/jcsm.13478"],"URL":"https:\/\/doi.org\/10.1002\/jcsm.13478","archive":["Portico"],"relation":{},"ISSN":["2190-5991","2190-6009"],"issn-type":[{"value":"2190-5991","type":"print"},{"value":"2190-6009","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,13]]},"assertion":[{"value":"2023-09-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}