{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T22:16:05Z","timestamp":1790115365922,"version":"4.0.1"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T00:00:00Z","timestamp":1715126400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Chronic subdural haematoma (CSDH) drainage is a common neurosurgical procedure. CSDHs cause excess mortality, which is exacerbated by frailty. Sarcopenia contributes to frailty \u2013 its key component, low muscle mass, can be assessed using cross\u2010sectional imaging. We aimed to examine the prognostic role of temporal muscle thickness (TMT) measured from preoperative computed tomography head scans among patients undergoing surgical CSDH drainage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively identified all patients who underwent CSDH drainage within 1\u00a0year of February 2019. We measured their mean TMT from preoperative computed tomography scans, tested the reliability of these measurements, and evaluated their prognostic value for postoperative survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and eighty\u2010eight (122, 65% males) patients (median age 78\u00a0years, IQR 70\u201385\u00a0years) were included. Thirty\u2010four (18%) patients died within 2\u00a0years, and 51 (27%) died at a median follow\u2010up of 39\u00a0months (IQR 34\u201342\u00a0months). Intra\u2010 and inter\u2010observer reliability of TMT measurements was good\u2010to\u2010excellent (ICC 0.85\u20130.97, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). TMT decreased with age (Pearson's <jats:italic>r<\/jats:italic>\u00a0=\u00a0\u22120.38, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Females had lower TMT than males (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). The optimal TMT cut\u2010off values for predicting two\u2010year survival were 4.475\u00a0mm for males and 3.125\u00a0mm for females. TMT below these cut\u2010offs was associated with shorter survival in both univariate (HR 3.24, 95% CI 1.85\u20135.67) and multivariate (HR 1.86, 95% CI 1.02\u20133.36) analyses adjusted for age, ASA grade and bleed size. The effect of TMT on mortality was not mediated by age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In patients with CSDH, TMT measurements from preoperative imaging were reliable and contained prognostic information supplemental to previously known predictors of poor outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcsm.13489","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T04:15:04Z","timestamp":1715228104000},"page":"1441-1450","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Reduced temporal muscle thickness predicts shorter survival in patients undergoing chronic subdural haematoma drainage"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5500-9200","authenticated-orcid":false,"given":"Tommi K.","family":"Korhonen","sequence":"first","affiliation":[{"name":"Division of Neurosurgery, Department of Clinical Neurosciences Cambridge University Hospitals NHS Foundation Trust &amp; University of Cambridge  Cambridge UK"},{"name":"Department of Neurosurgery, Neurocenter OYS Oulu University Hospital  Oulu Finland"},{"name":"Department of Neurosurgery, Research Unit of Clinical Neurosciences University of Oulu  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otso","family":"Arponen","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Cambridge  Cambridge UK"},{"name":"Faculty of Medicine and Health Sciences Tampere University  Tampere Finland"},{"name":"Department of Radiology Tampere University Hospital  Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1647-4481","authenticated-orcid":false,"given":"Moritz","family":"Steinruecke","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Clinical Neurosciences Cambridge University Hospitals NHS Foundation Trust &amp; University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilaria","family":"Pecorella","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Clinical Neurosciences Cambridge University Hospitals NHS Foundation Trust &amp; University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry","family":"Mee","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Clinical Neurosciences Cambridge University Hospitals NHS Foundation Trust &amp; University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Yordanov","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Clinical Neurosciences Cambridge University Hospitals NHS Foundation Trust &amp; University of Cambridge  Cambridge 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