{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T07:12:06Z","timestamp":1787987526354,"version":"build-2784847793"},"reference-count":40,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>It is well reported that malnutrition in acute care is associated with poorer health outcomes including increased mortality. However, the consequences of malnutrition on survival in community settings is uncertain. Malnutrition in people 65\u00a0years or over is often cited. Nevertheless, this study includes both middle\u2010aged and older adults as current public health policy is highlighting the need to increase disease\u2010free life years and is moving away from just extending life to increase overall longevity. The aim of this study is to describe the association of the risk of malnutrition using the Malnutrition Universal Screening Tool (MUST) with mortality in community\u2010dwelling middle\u2010aged and older adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We used the UK Biobank to investigate the association between those at risk of malnutrition and mortality in participants aged \u226550\u00a0years. MUST identified risk of malnutrition and linked data to national death registries confirmed mortality. Years of life lost (YLL) and Cox proportional hazard models with hazard ratios (HR) and confidence intervals (CI) described risk associated with all\u2010cause mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 502\u00a0408 participants recruited, 117\u00a0830 were \u226450\u00a0years leaving 384\u00a0578 eligible participants. Based on MUST scores 63\u00a0495 (16.5%) were at risk of malnutrition with 401 missing some data and excluded. Incidence of mortality for at risk participants was 755 per 100\u00a0000 person\u2010years, corresponding to 153\u00a0476 YLL. Of those at risk of malnutrition, 9.5% died versus 7.8% at low risk. Initial survival analysis reported an increased risk of mortality (HR 1.29, 95% CI: 1.25 to 1.33) that decreased after adjusting for confounders (HR 1.14, 95% CI: 1.11 to 1.18) in those at risk of malnutrition versus those at low risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Risk of malnutrition was associated with increased overall mortality. Modest effect sizes are demonstrated but are supportive of public health policies, which advocate wide\u2010scale community, based nutritional screening for middle\u2010aged and older adults.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcsm.13585","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T04:39:35Z","timestamp":1724992775000},"page":"2509-2518","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Overall mortality for community\u2010dwelling adults over 50\u00a0years at risk of malnutrition"],"prefix":"10.1002","volume":"15","author":[{"given":"Matthew","family":"Gittins","sequence":"first","affiliation":[{"name":"School of Health Sciences University of Manchester  Manchester UK"},{"name":"Manchester Academic Health Science Centre  Manchester 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