{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T14:15:14Z","timestamp":1787667314130,"version":"build-2736575974"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T00:00:00Z","timestamp":1732233600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T00:00:00Z","timestamp":1732233600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sarcopenia is a devastating disease for older adults, but it lacks accessible and reliable tools for measuring total appendicular skeletal muscle mass (ASMM). Two\u2010dimensional muscle ultrasound (US) has been developed for its bedside clinical advantages and feasibility but lacks standardization and prediction performance. We previously validated a new 3D\u2010US technique to measure muscle volume (MV) at bedside and applied it in a geriatric rehabilitation setting.<\/jats:p>\n                    <jats:p>Objectives were to analyse the concordance between 3D\u2010US MV and ASMM and compare concordance between 3D\u2010US MV and 2D\u2010US parameters with ASMM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Participants were recruited in a Geriatric rehabilitation ward in Nantes, France, from May to October 2022. Exclusion criteria were as follows: oedema in the lower limbs or recent history of unilateral lower limb damage or stroke. ASMM was measured with bioelectrical impedance analysis; 3D\u2010US and 2D\u2010US acquisitions were performed on three muscles of the right lower limb. Measures of strength (hand grip, knee extension and ankle dorsiflexion) were also recorded. Reliability of 3D\u2010US MV measurements on 10 participants was high (ICC\u2009=\u20090.99).<\/jats:p>\n                    <jats:p>We used Lin's concordance correlation coefficients (CCC) and bias correction factor for agreement between variables and linear regression models for prediction equations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifty\u2010eight participants had an interpretable ASMM of whom 17 (29%) had a diagnosis of sarcopenia. Volumes of TA, RF and VL were all significantly concordant with ASMM measured by BIA (all\n                      <jats:italic>p<\/jats:italic>\n                      values &lt;\u20090.001), with CCCs respectively of 0.72, 0.61 and 0.60. MV were all significantly concordant with isometric strength (\n                      <jats:italic>p<\/jats:italic>\n                      values &lt;\u20090.001). Concordance and correlation with ASMM were higher with 3D\u2010US than 2D\u2010US measurements regardless of the muscle. Prediction of ASMM reached an adjusted\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      of 0.8 with tibialis anterior volume, biometrics and 2D measurements.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study was the first to use 3D\u2010US in a geriatric setting and develop a model to predict ASMM in very old hospitalized patients. MV measurements with 3D\u2010US proved to be reliable and more concordant with appendicular muscle mass and strength than 2D parameters.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcsm.13648","type":"journal-article","created":{"date-parts":[[2024,11,22]],"date-time":"2024-11-22T05:44:01Z","timestamp":1732254241000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Concordance of Freehand 3D Ultrasound Muscle Measurements With Sarcopenia Parameters in a Geriatric Rehabilitation Ward"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3549-1378","authenticated-orcid":false,"given":"Jeremie","family":"Huet","sequence":"first","affiliation":[{"name":"Nantes Universit\u00e9, CHU Nantes, Movement \u2010 Interactions \u2010 Performance, MIP, UR 4334  Nantes France"},{"name":"Nantes Universit\u00e9, CHU Nantes, Pole de G\u00e9rontologie Clinique  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Nordez","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, CHU Nantes, Movement \u2010 Interactions \u2010 Performance, MIP, UR 4334  Nantes France"},{"name":"Institut Universitaire de France (IUF)  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lie","family":"Sarcher","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, CHU Nantes, Movement \u2010 Interactions \u2010 Performance, MIP, UR 4334  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Mathieu","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, CHU Nantes, Pole de G\u00e9rontologie Clinique  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Cornu","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, CHU Nantes, Movement 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