{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T07:50:20Z","timestamp":1775980220858,"version":"3.50.1"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T00:00:00Z","timestamp":1736467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T00:00:00Z","timestamp":1736467200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Falls and sarcopenia are significant public health issues in Vietnam. Despite muscle strength being a critical predictor for these conditions, reference data on muscle strength within the Vietnamese population are lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To establish the reference ranges for muscle strength among Vietnamese individuals.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The study involved 4096 individuals, including 1419 men and 2677 women aged 18\u2009years and above, from the Vietnam Osteoporosis Study. Muscle strength was assessed using a Baseline hand dynamometer for handgrip strength and a Back\u2010Leg\u2010Chest dynamometer for leg strength. We calculated mean values, standard deviations, interquartile ranges, and peak muscle strength (\n                      <jats:italic>p<\/jats:italic>\n                      MS) for both handgrip and leg strength across various ages. Reference curves were created with the Generalised Additive Model for Location Scale and Shape, and polynomial regression models were employed to analyse the relationship between muscle strength and age.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Advancing age was significantly associated with lower muscle strength. Peak muscle strength typically occurred between ages 30 and 40, with earlier peaks in women, especially in leg strength. Men consistently showed higher muscle strength than women, with variations depending on the measurement site. Specifically, average handgrip strength was 36.4\u2009kg\u2009\u00b1\u20098.4 (mean\u2009\u00b1\u2009SD) for men and 23.2\u2009kg\u2009\u00b1\u20096.0 for women (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Leg strength averaged 63.9\u2009kg\u2009\u00b1\u200927.2 for men and 29.5\u2009kg\u2009\u00b1\u200913.9 for women (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Additionally, we produced a percentile chart illustrating muscle weakness ranges based on the 25th percentile of muscle strength and the appendicular skeletal muscle mass index (ASMI) for the Vietnamese population.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These data provide reference ranges for evaluating muscle strength in the Vietnamese population, offering crucial insights for identifying individuals at risk of falls or sarcopenia in clinical settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcsm.13689","type":"journal-article","created":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T03:53:57Z","timestamp":1736481237000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Reference Values of Handgrip and Lower Extremity Strength for Vietnamese Men and Women: The Vietnam Osteoporosis Study"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-5978-5937","authenticated-orcid":false,"given":"Kiet\u00a0T.","family":"Do","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Le Van Thinh Hospital  Ho Chi Minh City Vietnam"},{"name":"Saigon Precision Medicine Research Center  Ho Chi Minh City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5621-5583","authenticated-orcid":false,"given":"Duy\u00a0K.","family":"Hoang","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering University of Technology Sydney  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quan\u00a0N.","family":"Luong","sequence":"additional","affiliation":[{"name":"Saigon Precision Medicine Research Center  Ho Chi Minh City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huy\u00a0G.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Saigon Precision Medicine Research Center  Ho Chi Minh City Vietnam"},{"name":"School of Biomedical Engineering University of Technology Sydney  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"An\u00a0T.","family":"Do","sequence":"additional","affiliation":[{"name":"Saigon Precision Medicine Research Center  Ho Chi Minh City Vietnam"},{"name":"Department of Internal Medicine Vinmec Central Park International Hospital  Ho Chi Minh City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8382-5080","authenticated-orcid":false,"given":"Lan\u00a0T.","family":"Ho\u2010Pham","sequence":"additional","affiliation":[{"name":"Saigon Precision Medicine Research Center  Ho Chi Minh City Vietnam"},{"name":"BioMedicine Research Center Pham Ngoc Thach University of Medicine  Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuan\u00a0V.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering University of Technology Sydney  Sydney Australia"},{"name":"Tam Anh Research Institute  Ho Chi Minh City Vietnam"},{"name":"School of Population Health UNSW Medicine UNSW Sydney  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3556"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afx094"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2016.09.013"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glz081"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afq034"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12567"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13383"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.14283\/jfa.2019.10"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12783"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.15304"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afy169"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2019.12.012"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afv192"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjpt.2019.10.001"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12112"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16071251"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.afos.2017.06.001"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.5040\/9781718220966"},{"key":"e_1_2_9_20_1","volume-title":"ACSM's Guidelines for Exercise Testing and Prescription","author":"American College of Sports M","year":"2010"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v023.i07"},{"key":"e_1_2_9_22_1","unstructured":"Core Team R \u201cA Language and Environment for Statistical Computing 2018 \u201d R Foundation for Statistical Computing; Vienna (2021) https:\/\/www.r\u2010project.org\/."},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1179\/108331905X55730"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1993.tb05949.x"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-019-00545-w"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2018.04.019"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/60.1.74"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-014-0528-y"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-016-0349-4"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)62000-6"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40814-016-0067-x"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113637"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12610"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0201275"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13223"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02982703"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e7279"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2012-091907"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001534"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsams.2017.03.021"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.52403\/ijshr.20210460"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1123\/japa.16.4.484"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12899"}],"container-title":["Journal of Cachexia, Sarcopenia and Muscle"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcsm.13689","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jcsm.13689","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcsm.13689","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T07:32:24Z","timestamp":1775979144000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcsm.13689"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,10]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1002\/jcsm.13689"],"URL":"https:\/\/doi.org\/10.1002\/jcsm.13689","archive":["Portico"],"relation":{},"ISSN":["2190-5991","2190-6009"],"issn-type":[{"value":"2190-5991","type":"print"},{"value":"2190-6009","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,10]]},"assertion":[{"value":"2024-04-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13689"}}