{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T13:58:12Z","timestamp":1790949492266,"version":"4.1.0"},"reference-count":89,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,4,20]],"date-time":"2025-04-20T00:00:00Z","timestamp":1745107200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mind\u2013body exercise (MBE) has shown promise in mitigating the effects of sarcopenia and frailty in older adults. Nevertheless, its effectiveness in enhancing muscle function and physical performance in this population has not been well established. This study aimed to investigate the effects of MBE on older adults with sarcopenia and frailty, to offer evidence\u2010based exercise recommendations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A comprehensive search for randomized controlled trials (RCTs) was conducted through multiple databases, including PubMed, Embase, Cochrane Library, Web of Science, PsycINFO, CINAHL, China National Knowledge Infrastructure (CNKI), WanFang, and Chinese Scientific Journals Full\u2010Text Database (VIP), supplemented by manual reference searches from inception until February 2024. The eligible RCTs compared MBE with passive or active exercise controls, focusing on muscle function and physical performance in older adults aged 60\u2009years or above. Subgroup analyses were conducted to evaluate the types, duration, and frequency of MBE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Nine eligible RCTs with 1838 participants were included in this study. MBE demonstrated significant improvements compared with passive control, particularly in grip strength (WMD [weighted mean difference]\u2009=\u20090.99; 95% CI [95% confidence interval]\u2009=\u20090.06, 1.92;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20093%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04), Timed Up and Go Test (TUGT) (WMD\u2009=\u2009\u22124.04; 95% CI\u2009=\u2009\u22125.54, \u22122.53;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200912%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01), and Berg Balance Scale (BBS) scores (WMD\u2009=\u20093.63; 95% CI\u2009=\u20090.38, 6.87;\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.03). Even when compared to active exercise training, improvements were still observed in TUGT and BBS (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with a trend toward improved grip strength (WMD\u2009=\u2009\u22122.20; 95% CI\u2009=\u2009\u22124.35, \u22120.04;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.05). No positive effect on muscle mass was observed. Subgroup analysis indicated that MBE performed more than 5 times a week for a short or medium duration (4\u201324\u2009weeks) could improve grip strength (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Moderate\u2010frequency intervention over a short period in this population yielded greater improvements in gait speed and Chair Rise Test completion time (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>MBE can enhance muscle function and physical performance to some extent in older adults with sarcopenia and frailty, whether they are compared with passive or active exercise training. However, positive effects on muscle mass have not been observed. Future studies are warranted to compare it with well\u2010designed active exercise training programs that match the exercise volume, to draw more definitive conclusions to support the notion that MBE yields comparable effects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcsm.13806","type":"journal-article","created":{"date-parts":[[2025,4,20]],"date-time":"2025-04-20T18:53:56Z","timestamp":1745175236000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Effectiveness of Mind\u2013Body Exercise in Older Adults With Sarcopenia and Frailty: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8249-8126","authenticated-orcid":false,"given":"Ruihan","family":"Wan","sequence":"first","affiliation":[{"name":"College of Rehabilitation Medicine Fujian University of Traditional Chinese Medicine Fuzhou  Fujian 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