{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T01:41:54Z","timestamp":1793410914076,"version":"4.5.0"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T00:00:00Z","timestamp":1745452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011724","name":"Muscular Dystrophy UK","doi-asserted-by":"publisher","award":["22GRO\u2010PG24\u20100575"],"award-info":[{"award-number":["22GRO\u2010PG24\u20100575"]}],"id":[{"id":"10.13039\/100011724","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011724","name":"Muscular Dystrophy UK","doi-asserted-by":"publisher","award":["24GRO\u2010PG24\u20100736\u20101"],"award-info":[{"award-number":["24GRO\u2010PG24\u20100736\u20101"]}],"id":[{"id":"10.13039\/100011724","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012295","name":"NIHR Newcastle Biomedical Research Centre","doi-asserted-by":"publisher","award":["NIHR203309"],"award-info":[{"award-number":["NIHR203309"]}],"id":[{"id":"10.13039\/501100012295","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Neuromuscular diseases (NMDs) are rare disorders characterized by progressive muscle fibre loss, leading to replacement by fibrotic and fatty tissue, muscle weakness and disability. Early diagnosis is critical for therapeutic decisions, care planning and genetic counselling. Muscle magnetic resonance imaging (MRI) has emerged as a valuable diagnostic tool by identifying characteristic patterns of muscle involvement. However, the increasing complexity of these patterns complicates their interpretation, limiting their clinical utility. Additionally, multi\u2010study data aggregation introduces heterogeneity challenges. This study presents a novel multi\u2010study harmonization pipeline for muscle MRI and an AI\u2010driven diagnostic tool to assist clinicians in identifying disease\u2010specific muscle involvement patterns.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We developed a preprocessing pipeline to standardize MRI fat content across datasets, minimizing source bias. An ensemble of XGBoost models was trained to classify patients based on intramuscular fat replacement, age at MRI and sex. The SHapley Additive exPlanations (SHAP) framework was adapted to analyse model predictions and identify disease\u2010specific muscle involvement patterns. To address class imbalance, training and evaluation were conducted using class\u2010balanced metrics. The model's performance was compared against four expert clinicians using 14 previously unseen MRI scans.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Using our harmonization approach, we curated a dataset of 2961 MRI samples from genetically confirmed cases of 20 paediatric and adult NMDs. The model achieved a balanced accuracy of 64.8%\u2009\u00b1\u20093.4%, with a weighted top\u20103 accuracy of 84.7%\u2009\u00b1\u20091.8% and top\u20105 accuracy of 90.2%\u2009\u00b1\u20092.4%. It also identified key features relevant for differential diagnosis, aiding clinical decision\u2010making. Compared to four expert clinicians, the model obtained the highest top\u20103 accuracy (75.0%\u2009\u00b1\u20094.8%). The diagnostic tool has been implemented as a free web platform, providing global access to the medical community.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The application of AI in muscle MRI for NMD diagnosis remains underexplored due to data scarcity. This study introduces a framework for dataset harmonization, enabling advanced computational techniques. Our findings demonstrate the potential of AI\u2010based approaches to enhance differential diagnosis by identifying disease\u2010specific muscle involvement patterns. The developed tool surpasses expert performance in diagnostic ranking and is accessible to clinicians worldwide via the Myo\u2010Guide online platform.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcsm.13815","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T02:26:23Z","timestamp":1745547983000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Myo\u2010Guide: A Machine Learning\u2010Based Web Application for Neuromuscular Disease Diagnosis With MRI"],"prefix":"10.1002","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5631-0030","authenticated-orcid":false,"given":"Jose","family":"Verdu\u2010Diaz","sequence":"first","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Bolano\u2010D\u00edaz","sequence":"additional","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Gonzalez\u2010Chamorro","sequence":"additional","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Fitzsimmons","sequence":"additional","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jodi","family":"Warman\u2010Chardon","sequence":"additional","affiliation":[{"name":"Department of Medicine (Neurology) The Ottawa Hospital  Ottawa Canada"},{"name":"Department of Genetics Children's Hospital of Eastern Ontario  Ottawa Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goknur\u00a0Selen","family":"Kocak","sequence":"additional","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debora","family":"Mucida\u2010Alvim","sequence":"additional","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian\u00a0C.","family":"Smith","sequence":"additional","affiliation":[{"name":"Ottawa Hospital Research Institute  Ottawa Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Vissing","sequence":"additional","affiliation":[{"name":"Copenhagen Neuromuscular Centre, Rigshospitalet Copenhagen University Hospital  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanna\u00a0Scharff","family":"Poulsen","sequence":"additional","affiliation":[{"name":"Copenhagen Neuromuscular Centre, Rigshospitalet Copenhagen University Hospital  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sushan","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Neurology, Huashan Hospital Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Dom\u00ednguez\u2010Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Neuromuscular Disorders Unit, Neurology Department Hospital 12 de Octubre  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Bermejo\u2010Guerrero","sequence":"additional","affiliation":[{"name":"Neuromuscular Disorders Unit, Neurology Department Hospital 12 de Octubre  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Gomez\u2010Andres","sequence":"additional","affiliation":[{"name":"Hospital Universitari Vall d'Hebron  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Sotoca","sequence":"additional","affiliation":[{"name":"Neuromuscular Disorders Unit, Neurology Department Hospital Universitari Vall d'Hebron  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Pichiecchio","sequence":"additional","affiliation":[{"name":"Department of Brain and Behavioural Sciences University of Pavia  Pavia Italy"},{"name":"Advanced Imaging and AI Center Mondino IRCCS Foundation  Pavia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Nicolosi","sequence":"additional","affiliation":[{"name":"University of Pavia; Mondino IRCCS Foundation  Pavia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Monforte","sequence":"additional","affiliation":[{"name":"UOC di Neurologia Fondazione Policlinico Universitario Agostino Gemelli IRCCS  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Brogna","sequence":"additional","affiliation":[{"name":"Fondazione Policlinico Universitario Agostino Gemelli  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenio","family":"Mercuri","sequence":"additional","affiliation":[{"name":"Pediatric Neurology, Department of Woman and Child Health and Public Health, Child Health Area Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge\u00a0Alfredo","family":"Bevilacqua","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universidad de Chile  Santiago de Chile Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"D\u00edaz\u2010Jara","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universidad de Chile  Santiago de Chile Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjam\u00edn","family":"Pizarro\u2010Galleguillos","sequence":"additional","affiliation":[{"name":"Programa de Doctorado en Ciencias M\u00e9dicas y Especialidad Escuela de Postgrado Facultad de Medicina Universidad de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Krkoska","sequence":"additional","affiliation":[{"name":"University Hospital Brno  Brno Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Alonso\u2010P\u00e9rez","sequence":"additional","affiliation":[{"name":"Neuromuscular Disease Unit, Neurology Department Hospital Universitario Nuestra Se\u00f1ora de Candelaria  Tenerife Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montse","family":"Oliv\u00e9","sequence":"additional","affiliation":[{"name":"Neuromuscular Disorders Unit, Department of Neurology Hospital de la Santa Creu i Sant Pau  Barcelona Spain"},{"name":"Biomedical Research Institute Sant Pau (IIB Sant Pau)  Barcelona Spain"},{"name":"Centro de Investigaciones Biom\u00e9dicas en Red en Enfermedades Raras (CIBERER)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik\u00a0H.","family":"Niks","sequence":"additional","affiliation":[{"name":"Department of Neurology Leiden University Medical Center  Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermien\u00a0E.","family":"Kan","sequence":"additional","affiliation":[{"name":"C.J. Gorter MRI Center, Department of Radiology Leiden University Medical Center  Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Lilleker","sequence":"additional","affiliation":[{"name":"Northern Care Alliance NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Roberts","sequence":"additional","affiliation":[{"name":"Northern Care Alliance NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Buchignani","sequence":"additional","affiliation":[{"name":"Department of Translational Research and of New Surgical and Medical Technologies University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhong","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Neurology Pusan National University School of Medicine  Busan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Esselin","sequence":"additional","affiliation":[{"name":"Centre de R\u00e9f\u00e9rence des Maladies du Motoneurone, Department of Neurology Montpellier University Hospital  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Le\u00a0Bars","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, I2FH Platform Montpellier University Hospital  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne\u00a0Marie","family":"Childs","sequence":"additional","affiliation":[{"name":"Leeds Teaching Hospitals NHS Trust  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edoardo","family":"Malfatti","sequence":"additional","affiliation":[{"name":"Paris Est University, APHP Henri\u2010Mondor University Hospital  Cr\u00e9teil France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Sarkozy","sequence":"additional","affiliation":[{"name":"Dubowitz Neuromuscular Centre UCL Great Ormond Street Institute of Child Health &amp; Great Ormond Street Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke","family":"Perry","sequence":"additional","affiliation":[{"name":"Dubowitz Neuromuscular Centre UCL Great Ormond Street Institute of Child Health &amp; Great Ormond Street Hospital  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sniya","family":"Sudhakar","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Great Ormond Street Hospital for Children NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edmar","family":"Zanoteli","sequence":"additional","affiliation":[{"name":"Department of Neurology Faculdade de Medicina da Universidade de S\u00e3o Paulo (FMUSP)  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filipe\u00a0Tupinamba","family":"Di\u00a0Pace","sequence":"additional","affiliation":[{"name":"Department of Neurology Faculdade de Medicina da Universidade de S\u00e3o Paulo (FMUSP)  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Matthews","sequence":"additional","affiliation":[{"name":"St George's University and St George's University Hospitals NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahram","family":"Attarian","sequence":"additional","affiliation":[{"name":"Reference Center for Neuromuscular Disorders CHU La Timone, Aix\u2010Marseille University  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Bendahan","sequence":"additional","affiliation":[{"name":"Aix\u2010Marseille University, CRMBM, CNRS UMR 7339  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Garibaldi","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Mental Health and Sensory Organs (NESMOS) SAPIENZA University of Rome  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Fionda","sequence":"additional","affiliation":[{"name":"Neuromuscular and Rare Disease Centre, Neurology Unit, Sant'Andrea Hospital  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Alonso\u2010Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Neuromuscular Reference Center, Department of Neurology, Universitair Ziekenhuis van Antwerpen Universiteit Antwerpen  Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Carlier","sequence":"additional","affiliation":[{"name":"University Hospital Raymond\u2010Poincar\u00e9  Garches France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali\u00a0Asghar","family":"Okhovat","sequence":"additional","affiliation":[{"name":"Neurology Department, Shariati Hospital, Neuromuscular Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahriar","family":"Nafissi","sequence":"additional","affiliation":[{"name":"Neurology Department, Shariati Hospital, Neuromuscular Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atchayaram","family":"Nalini","sequence":"additional","affiliation":[{"name":"National Institute of Mental Health and Neurosciences (NIMHANS)  Bengaluru India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seena","family":"Vengalil","sequence":"additional","affiliation":[{"name":"National Institute of Mental Health and Neurosciences (NIMHANS)  Bengaluru India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kieren","family":"Hollingsworth","sequence":"additional","affiliation":[{"name":"Translational and Clinical Research Institute Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Marini\u2010Bettolo","sequence":"additional","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Straub","sequence":"additional","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Tasca","sequence":"additional","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaume","family":"Bacardit","sequence":"additional","affiliation":[{"name":"Interdisciplinary Computing and Complex BioSystems (ICOS) Research Group, School of Computing Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2941-7988","authenticated-orcid":false,"given":"Jordi","family":"D\u00edaz\u2010Manera","sequence":"additional","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Myo\u2010Guide Consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61897-2"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000851"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.25804"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-017-8547-3"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2017.06.011"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8966(02)00023-8"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2017-316736"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2018.00456"},{"issue":"2","key":"e_1_2_9_10_1","article-title":"Muscle MRI in Muscular Dystrophies","volume":"34","author":"D\u00edaz\u2010Manera J.","year":"2015","journal-title":"Acta Myologica"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-020-0346-2"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2023.1251025"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-89311-3"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-021-10786-1"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2023.11.004"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000009068"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-023-11862-4"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2019.08.011"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1010933404324"},{"key":"e_1_2_9_20_1","doi-asserted-by":"crossref","unstructured":"J.LaaksonenandE.Oja \u201cClassification With Learning k\u2010Nearest Neighbors \u201d inProceedings of International Conference on Neural Networks (ICNN'96) (1996):1480\u20131483.","DOI":"10.1109\/ICNN.1996.549118"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.16207"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1145\/2907070"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42256-019-0138-9"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000011231"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-011-6357-6"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.52.1.176"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.27638"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2023.07.005"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10334-021-00967-4"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2020.109460"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2022.110260"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2012.05.012"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000008811"},{"key":"e_1_2_9_34_1","unstructured":"S.NicolauandE.Naddaf \u201cMuscle MRI for Neuromuscular Disorders Using Muscle MRI to Diagnose Neuromuscular Conditions Requires Awareness of Different Patterns of Muscle Involvement \u201d (2020)."},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.27947"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25035"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24661"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2005.01.004"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43588-021-00086-z"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.2019.1632079"},{"issue":"2","key":"e_1_2_9_41_1","first-page":"631","article-title":"Imputed Factor Regression for High\u2010Dimensional Block\u2010Wise Missing Data","volume":"30","author":"Zhang Y.","year":"2020","journal-title":"Statistica Sinica"}],"container-title":["Journal of Cachexia, Sarcopenia and Muscle"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcsm.13815","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T06:23:51Z","timestamp":1750832631000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcsm.13815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,24]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1002\/jcsm.13815"],"URL":"https:\/\/doi.org\/10.1002\/jcsm.13815","archive":["Portico"],"relation":{},"ISSN":["2190-5991","2190-6009"],"issn-type":[{"value":"2190-5991","type":"print"},{"value":"2190-6009","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,24]]},"assertion":[{"value":"2024-09-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13815"}}