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This underscores the need for universal recommendations that address the unique challenges faced by patients and healthcare providers worldwide. Our Global Guidelines emphasise the incorporation of novel therapies while integrating standards of care with the most up\u2010to\u2010date evidence to enable clinicians to optimise obesity management. Context\u2010specific recommendations tailored to individual patient needs are highlighted, providing a thorough evaluation of the risks, benefits and overall value of each therapy, aiming to establish a standard of care that improves patient outcomes and reduces the burden of hospitalisation in this susceptible population. 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