{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:59:20Z","timestamp":1791244760738,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R01AG067758"],"award-info":[{"award-number":["R01AG067758"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT1174886"],"award-info":[{"award-number":["GNT1174886"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001778","name":"Deakin University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001778","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J cachexia sarcopenia muscle"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Sarcopenia is associated with impaired physical function. Dual\u2010task conditions, which increase cognitive demand during motor performance, may reveal deficits in neuromuscular control that are not evident during isolated motor tasks. We investigated whether older adults with sarcopenia exhibit poorer force and neural control (i.e., greater force and motor unit inter\u2010spike variability and altered common synaptic input) during single\u2010 and dual\u2010task conditions compared with non\u2010sarcopenic controls and masters athletes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Sarcopenia was defined using Sarcopenia Definitions and Outcomes Consortium criteria (low grip strength and slow gait). Participants (11 sarcopenic, 22 controls and 19 masters athletes; 74.3\u2009\u00b1\u20097.3\u2009years; 50% female) performed sustained isometric ankle dorsiflexion contractions at 30% of maximal voluntary torque, without (single\u2010task) and with concurrent serial number subtraction (dual\u2010task). Motor unit spike trains were decomposed from high\u2010density surface electromyograms. Outcomes included torque and inter\u2010spike interval coefficient of variation (index of discharge regularity linked to torque steadiness) and intramuscular coherence: delta (1\u20135\u2009Hz; low\u2010frequency common input related to force fluctuations), alpha (5\u201315\u2009Hz; which may include tremor\u2010related, spinal and afferent contributions) and beta (15\u201335\u2009Hz; commonly associated with corticospinal input) bands.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Individuals with sarcopenia had higher torque coefficient of variation (worse steadiness) than controls in single\u2010 and dual\u2010task by 45% and 84% and athletes by 39% and 105%, respectively. In individuals with sarcopenia, coefficient of variation rose ~35% from single\u2010 to dual\u2010task. Mean discharge rate (a proxy of neural drive) increased ~2.6% during dual\u2010tasking in all groups, without between\u2010group differences. Inter\u2010spike interval coefficient of variation increased by 5.5% in sarcopenic, was unchanged in controls and decreased 4.1% in athletes. Delta\u2010band coherence decreased 5.5% across all groups, whereas alpha\u2010band coherence increased in sarcopenic only (20.6%). Beta\u2010band coherence increased 14.5% in sarcopenic but decreased 8.4% in controls and 13.3% in athletes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Older adults with sarcopenia exhibit poorer force and neural control steadiness, and both deficits worsen under cognitive load. These changes are accompanied by alterations in common synaptic input, particularly increases in alpha and beta bands in individuals with sarcopenia, likely contributing to their greater force unsteadiness during dual\u2010tasking. Neural control unsteadiness during dual\u2010task performance may therefore represent a neural feature of sarcopenia\u2010related functional impairment. Assessing neuromuscular control during cognitively demanding tasks may improve detection of neural dysfunction and identify mechanistic targets for interventions aimed at preserving mobility in older adults. These findings support expanding muscle\u2010centric views of sarcopenia to include neural mechanisms of motor control.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcsm.70397","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:43:56Z","timestamp":1791243836000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dual\u2010Tasking Exacerbates Force and Neural Control Unsteadiness in Older Adults With Sarcopenia"],"prefix":"10.1002","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3788-3700","authenticated-orcid":false,"given":"Lucas B. R.","family":"Orssatto","sequence":"first","affiliation":[{"name":"Centre for Sensorimotor Performance, School of Human Movement and Nutrition Sciences The University of Queensland  Brisbane Queensland Australia"},{"name":"Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences Deakin University  Burwood Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6021-6431","authenticated-orcid":false,"given":"Brian C.","family":"Clark","sequence":"additional","affiliation":[{"name":"Ohio Musculoskeletal and Neurological Institute (OMNI) Ohio University  Athens Ohio USA"},{"name":"Department of Biomedical Sciences, Heritage College of Osteopathic Medicine Ohio University  Athens Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5226-1972","authenticated-orcid":false,"given":"David","family":"Scott","sequence":"additional","affiliation":[{"name":"Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences Deakin University  Burwood Victoria Australia"},{"name":"Department of Medicine, School of Clinical Sciences at Monash Health Monash University  Clayton Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3252-0724","authenticated-orcid":false,"given":"H\u00e9lio V.","family":"Cabral","sequence":"additional","affiliation":[{"name":"School of Physical Education and Sports Universidade Federal do Rio de Janeiro  Rio de Janeiro Brazil"},{"name":"Biomedical Engineering Program (COPPE) Universidade Federal do Rio de Janeiro  Rio de Janeiro Brazil"},{"name":"Postgraduate Program in Rehabilitation Sciences Universidade Federal do Rio de Janeiro  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1941-3900","authenticated-orcid":false,"given":"Gabriel L.","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Physical Activity, Sport and Exercise Research (PASER) Theme, Faculty of Health Southern Cross University  Gold Coast Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9897-1598","authenticated-orcid":false,"given":"Robin M.","family":"Daly","sequence":"additional","affiliation":[{"name":"Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences Deakin University  Burwood Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41572-024-00550-w","article-title":"Sarcopenia","volume":"10","author":"Sayer A. 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