{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T02:04:43Z","timestamp":1771293883090,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2001,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report the sonographic diagnosis of Neu\u2010Laxova syndrome in a fetus at 27 weeks' menstrual age. The parents were first cousins. Sonography revealed microcephaly, a sloping forehead, exophthalmos, a small thorax and abdomen, hypoplastic lungs, syndactyly, hyperextended knees, polyhydramnios, a small placenta, and intrauterine growth restriction. The long bones were normal. The calvaria was hyperechoic and associated with shadowing, obscuring any intracranial abnormalities. This sonographic finding was presumed to represent calvarial calcification, not previously described with this syndrome. We believe that Neu\u2010Laxova syndrome can be reliably diagnosed prenatally by demonstrating the sonographic features described, although other conditions with similar sonographic features need to be considered in the differential diagnosis. \u00a9 2001 John Wiley &amp; Sons, Inc. J Clin Ultrasound 29:531\u2013534, 2001.<\/jats:p>","DOI":"10.1002\/jcu.10019","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T19:52:11Z","timestamp":1030305131000},"page":"531-534","source":"Crossref","is-referenced-by-count":16,"title":["Prenatal sonographic diagnosis of Neu\u2010Laxova syndrome"],"prefix":"10.1002","volume":"29","author":[{"family":"Durr\u2010e\u2010Sabih","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali N.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahida","family":"Sabih","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,11]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1542\/peds.47.3.610","article-title":"A lethal syndrome of microcephaly with multiple congenital anomalies in three siblings","volume":"47","author":"Neu RL","year":"1971","journal-title":"Pediatrics"},{"key":"e_1_2_1_3_2","first-page":"139","article-title":"A further example of a lethal autosomal recessive condition in sibs","volume":"16","author":"Laxova R","year":"1972","journal-title":"J Ment Defic Res"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320030304"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/15513819509026940"},{"key":"e_1_2_1_6_2","first-page":"132","volume-title":"Ultrasound of fetal syndromes","author":"Benacerraf BR","year":"1998"},{"key":"e_1_2_1_7_2","unstructured":"JeantyP SilvaSR. 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