{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T10:54:03Z","timestamp":1700564043689},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2007,5,7]],"date-time":"2007-05-07T00:00:00Z","timestamp":1178496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose.<\/jats:title><jats:p>To determine the optimal crown\u2013rump length (CRL) for obtaining nuchal translucency (NT) measurements.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>Women undergoing NT measurements by NT\u2010certified sonographers within a combined screening program over an 18\u2010month period were included in the study if they had a living fetus with a CRL of 45\u201384 mm. NT measurement success and screen\u2010positive rates, transvaginal sonography (TVUS) use, and reasons for failed NT measurements were compared in 3 groups by CRL corresponding to 11\u20100\/7 to 11\u20106\/7 weeks (45\u201354 mm), 12\u20100\/7 to 12\u20106\/7 weeks (55\u201366 mm), and 13\u20100\/7 to 13\u20106\/7 weeks (67\u201384 mm).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Eight hundred thirty\u2010seven women aged 34.9 \u00b1 4.9 years underwent 1 to 3 NT measurements at a mean CRL of 59.8 \u00b1 25.0 mm. NT measurements were more successful at 11 and 12 weeks (81.8% and 84.4%) than at 13 weeks (66.9%) (<jats:italic>p<\/jats:italic> &lt; 0.001). Screen\u2010positive and TVUS rates, and reasons for failed NT measurements did not vary by CRL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>NT measurements are most successful at CRL 45\u201366 mm corresponding to sonographically determined gestational ages of 11\u20100\/7 to 12\u20106\/7 weeks. \u00a9 2007 Wiley Periodicals, Inc. 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