{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T04:24:25Z","timestamp":1786595065878,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2007,5,7]],"date-time":"2007-05-07T00:00:00Z","timestamp":1178496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2007,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose.<\/jats:title><jats:p>Ultrasound\u2010guided core needle biopsy for the diagnosis and management of malignant lymphomas is controversial and has not been accepted as an alternative to surgical biopsy. We investigate the clinical usefulness of this procedure in a large series of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>Over a 5\u2010year period (2000\u20132004), ultrasound\u2010guided core needle biopsies were performed in 102 malignant lymphomas. Five diagnostic categories were considered: large B\u2010cell lymphomas (LBCL), small B\u2010cell lymphomas (SBCL), Hodgkin's disease (HD), T cell lymphomas, and miscellaneous. Surgical excisional biopsy of the node was performed in 47 cases (46.1%) for diagnostic confirmation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>The overall diagnostic accuracy of ultrasound\u2010guided core needle biopsy was 88.2% (90\/102). SBCL (39), LBCL (36), HD (15), T cell lymphomas (5), and miscellaneous (7) [including T cell\u2013rich B cell (2), natural killer cell (1), Burkitt's lymphoma (1), and non\u2010Hodgkin's lymphoma of the B cell type, NOS (3)] were correctly diagnosed. Three HDs, 1 natural killer cell lymphoma, 1 follicular lymphoma, and 1 LBCL were not correctly diagnosed. The core needle biopsy did not yield tumor tissue in 6 cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions.<\/jats:title><jats:p>Ultrasound\u2010guided core needle biopsy is effective in the diagnosis of malignant lymphomas and can be used as the first diagnostic approach in selected clinical situations. \u00a9 2007 Wiley Periodicals, Inc. J Clin Ultrasound, 2007<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.20383","type":"journal-article","created":{"date-parts":[[2007,5,7]],"date-time":"2007-05-07T19:46:27Z","timestamp":1178567187000},"page":"295-301","source":"Crossref","is-referenced-by-count":50,"title":["Value of ultrasound\u2010guided core biopsy in the diagnosis of malignant lymphoma"],"prefix":"10.1002","volume":"35","author":[{"given":"Aitor Fern\u00e1ndez","family":"de Larrinoa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"del 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