{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T09:33:17Z","timestamp":1781602397664,"version":"3.54.5"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2007,12,7]],"date-time":"2007-12-07T00:00:00Z","timestamp":1196985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2008,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To use 3\u2010dimensional sonography (3DUS) to measure contralateral lung volume and evaluate the potential of this measurement to predict neonatal outcome in isolated congenital diaphragmatic hernia (CDH).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between January 2002 and December 2004, the contralateral lung volumes of 39 fetuses with isolated CDH were measured via 3DUS using rotational multiplanar imaging. The observed\/expected contralateral fetal lung volume ratios (o\/e\u2010ContFLVR) were compared with the lung\/head ratio (LHR), observed\/expected total fetal lung volume ratio (o\/e\u2010TotFLVR), and postnatal outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Contralateral lung volumes are less reduced than total lung volumes in CDH. The bias and precision of 3DUS in estimating contralateral lung volumes were 0.99 cm<jats:sup>3<\/jats:sup> and 1.11 cm<jats:sup>3<\/jats:sup>, respectively, with absolute limits of agreement ranging from \u22121.19 cm<jats:sup>3<\/jats:sup> to +3.17 cm<jats:sup>3<\/jats:sup>. The o\/e\u2010ContFLVR was significantly lower in neonatal death cases (median, 0.49 cm<jats:sup>3<\/jats:sup>; range, 0.22\u20130.99 cm<jats:sup>3<\/jats:sup>) than in survival cases (median, 0.58 cm<jats:sup>3<\/jats:sup>; range, 0.42\u20130.92 cm<jats:sup>3<\/jats:sup> [<jats:italic>p<\/jats:italic> &lt; 0.01]). Overall accuracy of the o\/e\u2010ContFLVR, o\/e\u2010TotFLVR, and LHR in predicting neonatal death were 67.7% (21\/31), 80.7% (25\/31), and 77.4% (24\/31), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although o\/e\u2010ContFLVR can be precisely measured with 3DUS and can be used to predict neonatal death in CDH, it is less accurate than LHR and o\/e\u2010TotFLVR for that purpose. \u00a9 2007 Wiley Periodicals, Inc. 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