{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T06:06:33Z","timestamp":1768889193283,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2010,4,29]],"date-time":"2010-04-29T00:00:00Z","timestamp":1272499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim was to assess the value of ultrasound (US) in differentiating benign from malignant parotid gland lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>During a 3\u2010year period, US\u2010guided fine\u2010needle aspiration biopsy was performed on 89 parotid lesions with a size \u22655 mm in 68 patients. In 80 (90%) lesions, specimens were adequate for cytologic analysis. We recorded the seven following US parameters: size, number, echogenicity, echotexture, margins' clarity, distal acoustic enhancement, and regional lymph node enlargement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fine\u2010needle aspiration biopsy revealed 18 (22%) malignant tumors, 30 (38%) benign tumors, and 32 (40%) nonneoplastic lesions. The mean size of the malignant tumors was 25 \u00b1 17 mm versus 27 \u00b1 17 mm for benign tumors versus 21 \u00b1 12 mm for nonneoplastic lesions (<jats:italic>p<\/jats:italic> &gt; 0.05). Among 33 solitary tumors, 9 were malignant tumors and 24 were benign tumors. The majority of the parotid lesions were hypoechoic. The US feature that was most often associated with a benign lesion was distal acoustic enhancement. The US features that suggested malignancy were a heterogeneous echotexture, indistinct margins, and regional lymph node enlargement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>US can aid in the differentiation of parotid gland tumors, although benign and malignant parotid tumors often have a similar sonographic appearance. \u00a9 2010 Wiley Periodicals, Inc. J Clin Ultrasound, 2010<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.20704","type":"journal-article","created":{"date-parts":[[2010,4,30]],"date-time":"2010-04-30T11:03:00Z","timestamp":1272625380000},"page":"294-298","source":"Crossref","is-referenced-by-count":37,"title":["Sonographic diagnosis of parotid gland lesions: Correlation with the results of sonographically guided fine\u2010needle aspiration biopsy"],"prefix":"10.1002","volume":"38","author":[{"given":"Dragica Obad","family":"Kova\u010devi\u0107","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris","family":"Fabijani\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,4,29]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/33081866"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2006.04.046"},{"key":"e_1_2_1_4_2","first-page":"144","article-title":"Fine needle aspiration biopsy in a diagnostic workup algorithm of salivary gland tumors","volume":"50","author":"Ivanova S","year":"2003","journal-title":"Neoplasma"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10434-001-0720-2"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.10015"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(99)70017-X"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(99)70120-4"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.10230"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.129.9.929"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.153.1.161"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.10026"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.20280"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.10015"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.10001"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.10205"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(20000425)90:2<111::AID-CNCR6>3.0.CO;2-N"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19980625)84:3<153::AID-CNCR6>3.0.CO;2-P"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s003300050576"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1258\/0022215054020421"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2004.23.6.777"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20581"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0347(200008)22:5<469::AID-HED5>3.0.CO;2-7"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215106004944"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/74329476"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.05.1549"},{"key":"e_1_2_1_27_2","first-page":"1608","article-title":"Ultrasonography\u2010guided core\u2010needle biopsy of parotid gland masses","volume":"25","author":"Wan YL","year":"2004","journal-title":"AJNR Am J Neuroradiol"}],"container-title":["Journal of Clinical Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjcu.20704","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.20704","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T06:39:09Z","timestamp":1700635149000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcu.20704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,29]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["10.1002\/jcu.20704"],"URL":"https:\/\/doi.org\/10.1002\/jcu.20704","archive":["Portico"],"relation":{},"ISSN":["0091-2751","1097-0096"],"issn-type":[{"value":"0091-2751","type":"print"},{"value":"1097-0096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4,29]]}}}