{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T11:14:32Z","timestamp":1718104472126},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2010,6,8]],"date-time":"2010-06-08T00:00:00Z","timestamp":1275955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2010,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose.<\/jats:title><jats:p>To compare gestational sac (GS) volume (GSV) between normal pregnancies and missed abortions and anembryonic pregnancies and to determine at what gestational age differences in GS volume become evident.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>GSV in missed abortion and anembryonic pregnancy were measured using three\u2010dimensional ultrasound and the results were compared with GSV in normal pregnancies. Pregnancies between 6 and 12<jats:sup>+6<\/jats:sup> gestational weeks of age according to last menstrual period were included in normal pregnancies, missed abortions, and anembryonic pregnancies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>There were 141 normal pregnancies and 82 missed or anembryonic abortions. GSV was significantly larger in normal pregnancies than in missed or anembryonic abortion: 27.51 \u00b1 25.25 cm<jats:sup>3<\/jats:sup> and 8.04 \u00b1 10.54 cm<jats:sup>3<\/jats:sup>, respectively (<jats:italic>p<\/jats:italic> &lt; 0.001). When stratified by weeks, statistically significant differences were found beginning at 7 weeks, while GSV measurements were not significantly different between the normal and abnormal pregnancies from 6 to 6<jats:sup>+6<\/jats:sup> weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion.<\/jats:title><jats:p>GSV in missed abortion and anembryonic pregnancies is significantly smaller than in normal pregnancies, starting at 7 weeks of gestational age. This finding may be helpful in the diagnosis of missed abortion or anembryonic pregnancies in selected cases. \u00a9 2010 Wiley Periodicals, Inc. 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