{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T07:50:16Z","timestamp":1720770616556},"reference-count":26,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2010,7,8]],"date-time":"2010-07-08T00:00:00Z","timestamp":1278547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose.<\/jats:title><jats:p>To evalute by Doppler sonography carotid and ocular hemodynamics in Beh\u00e7et disease with and without ocular involvement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods.<\/jats:title><jats:p>Seventy\u2010six patients with Beh\u00e7et disease (BD) were separated into three groups: with active uveitis, with inactive uveitis, and without uveitis, and compared with 23 controls. We used duplex Doppler sonography to measure peak systolic (PSV), end\u2010diastolic (EDV), and time\u2010averaged mean (Vmean) blood flow velocity in the ophthalmic, central retinal (CRA), temporal posterior ciliary, nasal posterior ciliary (NPCA), common carotid (CCA), internal carotid (ICA) arteries, and maximum flow velocity (Vmax) in the central retinal veins. We then calculated resistance and pulsatility indexes of all arteries. Comparisons were carried out by two\u2010way ANOVA and Holm\u2010Sidak method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results.<\/jats:title><jats:p>Only two patients (2.6%) had atherosclerotic plaques, without significant hemodynamic consequence. Patients with uveitis had significantly lower ICA PSV and EDV (<jats:italic>p<\/jats:italic> &lt; 0.05), and lower CRA PSV, EDV, and Vmean (<jats:italic>p<\/jats:italic> &lt; 0.001) than controls. Patients with active uveitis had lower NPCA PSV and EDV than patients without uveitis or controls (<jats:italic>p<\/jats:italic> &lt; 0.01). There were no differences in temporal posterior ciliary, ophthalmic, and CCA PSV, EDV, and in Vmean between groups (<jats:italic>p<\/jats:italic> &gt; 0.05). Patients with uveitis had lower central retinal veins Vmax than patients without uveitis and than controls (<jats:italic>p<\/jats:italic> &lt; 0.01). Resistance index, pulsatility index of retrobulbar arteries, CCA, and ICA were similar in the four groups (<jats:italic>p<\/jats:italic> &gt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions.<\/jats:title><jats:p>Patients with Beh\u00e7et disease and ocular involvement have lower CRA, CRV, NPCA, and ICA blood flow velocities than healthy volunteers. \u00a9 2010 Wiley Periodicals, Inc. 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