{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T12:29:35Z","timestamp":1759580975206},"reference-count":10,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2012,3,27]],"date-time":"2012-03-27T00:00:00Z","timestamp":1332806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective:<\/jats:title><jats:p>To compare the diagnostic value of transcranial color Doppler sonography (TCCS) with contrast\u2010enhanced transcranial color Doppler sonography (CE\u2010TCCS) for the detection and characterization of intracranial aneurysms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Thirty patients highly suspected of having an intracranial aneurysm were imaged using TCCS and CE\u2010TCCS. The ability to detect the aneurysms and determine their size and location accurately was compared with findings from digital subtraction angiography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>The overall sensitivity of CE\u2010TCCS was greater than that of TCCS (24\/30 versus 20\/30, respectively) (<jats:italic>p<\/jats:italic> = 0.125), but the difference was not significant. Neither TCCS nor CE\u2010TCCS could detect the three small (\u22645 mm diameter) aneurysms. The detection rate for larger aneurysms (5\u201315 mm diameter, n = 17) was nonsignificantly greater with CE\u2010TCCS (14\/17) than with TCCS (11\/17) (<jats:italic>p<\/jats:italic> = 0.438). Similarly, CE\u2010TCCS detected more large or giant aneurysms (&gt;16 mm diameter) than TCCS (10\/10 versus 9\/10, respectively) but the difference was not significant (<jats:italic>p<\/jats:italic> = 1.000). The benefit of contrast enhancement was identical for aneurysms \u226510 mm or &lt;10 mm in diameter. All (7\/7) middle cerebral artery aneurysms were detected by both TCCS and CE\u2010TCCS. CE\u2010TCCS yielded similar or slightly better results than TCCS for all other aneurysm locations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>CE\u2010TCCS can improve the sensitivity and detection rate of intracranial aneurysms \u22655 mm in size. \u00a9 2012 Wiley Periodicals, Inc. J Clin Ultrasound, 2012<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.21911","type":"journal-article","created":{"date-parts":[[2012,3,29]],"date-time":"2012-03-29T09:53:54Z","timestamp":1333014834000},"page":"535-539","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of transcranial color Doppler sonography without and with contrast enhancement for detection and characterization of intracranial aneurysms"],"prefix":"10.1002","volume":"40","author":[{"given":"Li\u2010Shu","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui\u2010qin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuo","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan\u2010li","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng\u2010lan","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong\u2010ying","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3,27]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.5.871"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199812103392401"},{"key":"e_1_2_5_4_2","first-page":"1401","article-title":"Neurologic complications of cerebral angiography","volume":"15","author":"Heiserman JE","year":"1994","journal-title":"Am J Neuroradiol"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.7863\/jum.1998.17.2.91"},{"key":"e_1_2_5_6_2","first-page":"509","article-title":"Contrast\u2010enhanced transcranial color\u2010coded duplexsonography in stroke patients with limited bone windows","volume":"21","author":"Gahn G","year":"2000","journal-title":"Am J Neuroradiol"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000063720"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.68.4.489"},{"key":"e_1_2_5_9_2","volume-title":"Echoenhancers and transcranial color duplex sonography","author":"Bogdahn U","year":"1998"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.68.4.489"},{"key":"e_1_2_5_11_2","first-page":"34","article-title":"The application of transcranial contrast\u2010enhanced ultrasound in intracranial arterial stenosis and occlusion disease","volume":"7","author":"Wen H","year":"2010","journal-title":"Chin J Med Ultrasound"}],"container-title":["Journal of Clinical Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjcu.21911","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.21911","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T04:07:22Z","timestamp":1696910842000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcu.21911"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,27]]},"references-count":10,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["10.1002\/jcu.21911"],"URL":"https:\/\/doi.org\/10.1002\/jcu.21911","archive":["Portico"],"relation":{},"ISSN":["0091-2751","1097-0096"],"issn-type":[{"value":"0091-2751","type":"print"},{"value":"1097-0096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,27]]}}}