{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T14:10:39Z","timestamp":1774534239977,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T00:00:00Z","timestamp":1401840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There are multiple causes of free\u2010floating thrombus (FFT) formation in carotid arteries. The purpose of this study was to evaluate the incidence and natural history of FFT in nonstenotic internal carotid arteries of patients with acute ischemic stroke.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>During a 50\u2010month period, 3,200 consecutive patients with acute ischemic stroke were evaluated for internal carotid artery stenosis and the presence of FFT by color\u2010coded duplex ultrasonography. Diagnostic workup included brain CT, transthoracic echocardiography, Holter electrocardiogram, and hypercoagulability state evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found an FFT in 5 (0.18%) of 2,757 patients with acute stroke and nonstenotic internal carotid artery (mean age 44 years). The underlying pathology was hypercoagulable state in active pulmonary tuberculosis (n\u2009=\u20091), essential thrombocythemia (n\u2009=\u20091), thrombotic complications of nonstenotic plaques (n\u2009=\u20091), unknown (n\u2009=\u20092). All patients clinically improved under antiplatelet therapy. Follow\u2010up color\u2010coded duplex ultrasonography showed complete dissolution of FFT in all cases. There was no stroke recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Internal carotid artery FFT could be found in young stroke patients without identifiable arterial disease and could be resolved with antithrombotic treatment \u00a9 2014 Wiley Periodicals, Inc. <jats:italic>J Clin Ultrasound<\/jats:italic> <jats:bold>43<\/jats:bold>:34\u201338, 2015<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.22172","type":"journal-article","created":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T12:09:19Z","timestamp":1401883759000},"page":"34-38","source":"Crossref","is-referenced-by-count":16,"title":["Free\u2010floating thrombus in stroke patients with nonstenotic internal carotid artery\u2014An ultrasonographic study"],"prefix":"10.1002","volume":"43","author":[{"given":"Evguenia","family":"Vassileva","sequence":"first","affiliation":[{"name":"Department of Neurology University Hospital \u201cTsaritsa Yoanna\u2013ISUL\u201d Sofia Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marin","family":"Daskalov","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital \u201cTsaritsa Yoanna\u2013ISUL\u201d Sofia Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paraskeva","family":"Stamenova","sequence":"additional","affiliation":[{"name":"Department of Neurology UMBALNP \u201cSaint Naum\u201d Sofia Bulgaria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,6,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2011.02.030"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-3019(86)90086-8"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.19.6.681"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2292030516"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.09.057"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000278696"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.9.1175"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.26.6.1114"},{"key":"e_1_2_5_10_1","first-page":"55","article-title":"Carotid thrombus formation and extension during anticoagulation: a case report of large vessel disease and hypercoagulable state in systemic sclerosis","volume":"107","author":"Renard D","year":"2007","journal-title":"Acta Neurol Belg"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.5.1002"},{"key":"e_1_2_5_12_1","first-page":"e78","article-title":"Switzer JA","volume":"76","year":"2011","journal-title":"Nichols FT. 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