{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:46:13Z","timestamp":1786977973410,"version":"build-2736575974"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T00:00:00Z","timestamp":1518393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["10411965300"],"award-info":[{"award-number":["10411965300"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Clinical decision making in children with heart disease relies on detailed measurements of cardiac structures using two\u2010dimensional and M\u2010mode echocardiography. However, no echocardiographic reference values are available for the Chinese children. We aimed to establish z\u2010score regression equations for left heart structures in a population\u2010based cohort of healthy Chinese Han children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Echocardiography was performed in 545 children with a normal heart. The dimensions of the aortic valve annulus (AVA), aortic sinuses of Valsalva (ASV), sinotubular junction (STJ), ascending aorta (AAO), left atrium (LA), mitral valve annulus (MVA), interventricular septal end\u2010diastolic thickness (IVSd), interventricular septal end\u2010systolic thickness (IVSs), left ventricular end\u2010diastolic diameter (LVIDd), left ventricular end\u2010systolic diameter (LVIDs), left ventricular posterior wall end\u2010diastolic thickness (LVPWd), left ventricular posterior wall end\u2010systolic thickness (LVPWs) were measured. Regression analyses were conducted to relate the measurements of left heart structures to body surface area (BSA). Left ventricular ejection fraction (LVEF) and left ventricular fractional shortening (LVFS) were calculated. Several models were used, and the adjusted R2 values were compared for each model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>AVA, ASV, STJ, AAO, LA, MVA, IVSd, IVSs, LVIDd, LVIDs, LVPWd, and LVPWs had a cubic relationship with BSA. LVEF and LVFS fell within a narrow range.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our results provide reference values for z scores and regression equations for left heart structures in Han Chinese children. These data may help make a quick and accurate judgment of the routine clinical measurement of left heart structures in children with heart disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jcu.22579","type":"journal-article","created":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T04:13:31Z","timestamp":1518408811000},"page":"328-333","source":"Crossref","is-referenced-by-count":11,"title":["Regression equations for calculation of z scores for echocardiographic measurements of left heart structures in healthy Han Chinese children"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9416-0050","authenticated-orcid":false,"given":"Shan\u2010Shan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Shanghai First Maternity and Infant Hospital Tongji University School of Medicine Shanghai 201204 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