{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:07:09Z","timestamp":1757704029155,"version":"3.41.2"},"reference-count":33,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,9,19]],"date-time":"2018-09-19T00:00:00Z","timestamp":1537315200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate whether repetitive measurements of speckle tracking echocardiography (STE)\u2010derived strain (S) and strain rate (SR) could reveal changes in left ventricular function in patients with nonischemic dilated cardiomyopathy treated with levosimendan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included 22 consecutive patients (age 53\u2009\u00b112\u2009years) with an ejection fraction (EF) below 35% and New York Heart Association (NYHA) class III\u2010IV symptoms that required intravenous inotropic support despite optimal medical therapy. The absence of any occlusive coronary artery disease was identified via previous coronary angiography in all patients. Echocardiographic variables, including strain\/strain rate, and NYHA functional class, were evaluated before and after levosimendan infusion at the 72nd hour and one month.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The strain and strain rate values for both left and right ventricles were observed to be increased NYHA functional class and left ventricular EF (<jats:italic>P<\/jats:italic>\u2009&lt;.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>STE can successfully completed conventional echocardiography in the evaluation of patients with decompensated heart failure who were treated with levosimendan.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.22627","type":"journal-article","created":{"date-parts":[[2018,9,19]],"date-time":"2018-09-19T12:13:50Z","timestamp":1537359230000},"page":"527-532","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Short\u2010term effects of levosimendan on strain\/strain rate markers in patients with nonischemic dilated cardiomyopathy"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9793-718X","authenticated-orcid":false,"given":"Tuncay","family":"K\u0131r\u0131\u015f","sequence":"first","affiliation":[{"name":"Department of Cardiology Izmir Katip Celebi University Ataturk Training and Research Hospital Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ey\u00fcp","family":"Avc\u0131","sequence":"additional","affiliation":[{"name":"Cardiology Department Balikesir University Faculty of Medicine Balikesir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0129282"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehjsup.2004.05.015"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2828(95)90009-8"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2003.12.006"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(01)01350-4"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1254\/jphs.CP0060010"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02570507"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-199506261-00009"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0091270002042001005"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.5414\/CPP40465"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.06.052"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.98.20.2141"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.08.016"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2007.05.018"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-7120-5-16"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.11.063"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jer021"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/2048872616687114"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2006.079707"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc0102.101396"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09455-2"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcha.2014.10.014"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.31729\/jnma.1628"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.114.000789"},{"key":"e_1_2_8_26_1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0022-3565(24)36366-9","article-title":"Ca sensitizers impair cardiac relaxation in failing human myocardium","volume":"280","author":"Hajjar RJ","year":"1997","journal-title":"J Pharmacol Exp Ther."},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-199505000-00016"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-0770(97)90252-4"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.1997.0806"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.03.092"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-010-0469-3"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.06.049"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1067\/mje.2002.116532"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2006.03.007"}],"container-title":["Journal of Clinical Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjcu.22627","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.22627","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T21:36:35Z","timestamp":1751924195000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcu.22627"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,19]]},"references-count":33,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1002\/jcu.22627"],"URL":"https:\/\/doi.org\/10.1002\/jcu.22627","archive":["Portico"],"relation":{},"ISSN":["0091-2751","1097-0096"],"issn-type":[{"type":"print","value":"0091-2751"},{"type":"electronic","value":"1097-0096"}],"subject":[],"published":{"date-parts":[[2018,9,19]]},"assertion":[{"value":"2017-12-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}