{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T19:22:58Z","timestamp":1792005778568,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T00:00:00Z","timestamp":1543795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Harlequin ichthyosis is the most severe form of autosomal recessive congenital ichthyoses. So far, there are only a few reports of prenatal diagnosis in the literature, as prenatal sonographic features are quite subtle. We report a case of prenatal diagnosis of Harlequin ichthyosis on third\u2010trimester sonographic examination in a consanguineous couple with no history of the disease and describe its characteristic sonographic features.<\/jats:p>","DOI":"10.1002\/jcu.22675","type":"journal-article","created":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T12:29:36Z","timestamp":1543840176000},"page":"228-231","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Prenatal sonographic diagnosis of Harlequin ichthyosis"],"prefix":"10.1002","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1470-184X","authenticated-orcid":false,"given":"Pedro","family":"Brand\u00e3o","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology Centro Hospitalar T\u00e2mega e Sousa  Penafiel 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