{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:18:33Z","timestamp":1747149513536,"version":"3.40.5"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,9,30]],"date-time":"2019-09-30T00:00:00Z","timestamp":1569801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012547","name":"Natural Science Foundation of Guangxi Zhuang Autonomous Region","doi-asserted-by":"publisher","award":["2013GXNSFAA019173"],"award-info":[{"award-number":["2013GXNSFAA019173"]}],"id":[{"id":"10.13039\/100012547","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This study aimed to analyze left ventricular (LV) remodeling in patients with LV dilation using three\u2010dimensional (3D) echocardiography, and to compare geometry and systolic function between patients with dilated cardiomyopathy (DCM) and with mitral regurgitation (MR) but similar LV dimension.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cross\u2010sectional study of 60 DCM and 60 MR patients with LV end diastolic diameter (LVEDD)\u2009&gt;\u200935\u2009mm\/m<jats:sup>2<\/jats:sup>, and of 60 healthy control volunteers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Despite a similar LVEDD, DCM patients showed a significantly higher 3D sphericity index (3D\u2010SI) than MR patients, whereas 3D ejection fraction (3D\u2010EF) was significantly lower (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01). There was a linear relationship between 3D\u2010EF and 3D\u2010SI in both DCM and MR patients (r = \u22120. 745 and r = \u22120. 642, respectively; both <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). Receiver operating characteristic (ROC) curves showed that 3D\u2010SI had could better discriminate between DCM and MR (sensitivity 90%; specificity 73%; AUC 0.852, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01) than other variables. The area under the ROC curve of 3D\u2010SI was significantly larger than that of 3D\u2010EF for detecting heart failure in both patients with DCM and MR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>LV geometry appears to be more spherical and associated with worse systolic function in DCM than in MR patients, in spite of similar LV dimensions. Systolic function correlated significantly with 3D\u2010SI, which provided a better description of LV remodeling and could be a stronger indicator of heart failure in patients with LV dilation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.22775","type":"journal-article","created":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T04:29:22Z","timestamp":1569904162000},"page":"29-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Three\u2010dimensional echocardiographic comparison of left ventricular geometry and systolic function between dilated cardiomyopathy and mitral regurgitation with similar left ventricular dilation"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0530-2679","authenticated-orcid":false,"given":"DeCai","family":"Zeng","sequence":"first","affiliation":[{"name":"Department of Ultrasonic Medicine First Affiliated Hospital of Guangxi Medical University  Nanning 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