{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:24:47Z","timestamp":1790735087324,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T00:00:00Z","timestamp":1589155200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"International Phlebology Union (UIP)-Bauerfeind","award":["Award 2015-2017"],"award-info":[{"award-number":["Award 2015-2017"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Lipedema is a chronic, common but underdiagnosed disease masquerading obesity, with female predominance, characterized by disproportional abnormal adipose tissue distribution of the lower and also upper extremities. The present study was designed to determine whether lipedema is associated with three\u2010dimensional (3D) speckle\u2010tracking echocardiography (3DSTE)\u2010derived left ventricular (LV) deformation abnormalities, and to assess the effects of 1\u2010hour use of medical compression stockings (MCS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The present study comprised 19 female patients with lipedema (mean age: 42.2\u2009\u00b1\u200912.4\u2009years), compared to 28 age\u2010matched healthy female controls (mean age: 42.0\u2009\u00b1\u20099.8\u2009years).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Lipedema patients showed larger left atrial and LV dimensions and greater LV ejection fraction than controls, without significant difference in other echocardiography variables. Lipedema patients had greater 3DSTE\u2010derived global and mean segmental LV circumferential and area strains than controls. Following 1\u2010hour use of wearing MCS, neither global and nor mean segmental LV strains showed significant impairment or improvement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Increased LV strains could be compensatory effects maintaining LV pumping function in lipedema. Short\u2010term wearing of MCS has no global effect on LV strains.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.22855","type":"journal-article","created":{"date-parts":[[2020,5,12]],"date-time":"2020-05-12T03:19:37Z","timestamp":1589253577000},"page":"470-475","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Are increased left ventricular strains compensatory effects in lipedema? Detailed analysis from the three\u2010dimensional speckle\u2010tracking echocardiographic MAGYAR\u2010Path Study"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7570-6214","authenticated-orcid":false,"given":"Attila","family":"Nemes","sequence":"first","affiliation":[{"name":"2nd Department of Medicine and Cardiology Centre, Faculty of Medicine, Albert Szent\u2010Gy\u00f6rgyi Clinical Center University of Szeged  Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1rp\u00e1d","family":"Korm\u00e1nyos","sequence":"additional","affiliation":[{"name":"2nd Department of Medicine and Cardiology Centre, Faculty of Medicine, Albert Szent\u2010Gy\u00f6rgyi Clinical Center University of Szeged  Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Domsik","sequence":"additional","affiliation":[{"name":"2nd Department of Medicine and Cardiology Centre, Faculty of Medicine, Albert Szent\u2010Gy\u00f6rgyi Clinical Center University of Szeged  Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Kalapos","sequence":"additional","affiliation":[{"name":"2nd Department of Medicine and Cardiology Centre, Faculty of Medicine, Albert Szent\u2010Gy\u00f6rgyi Clinical Center University of Szeged  Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N\u00e1ndor","family":"Gyenes","sequence":"additional","affiliation":[{"name":"2nd Department of Medicine and Cardiology Centre, Faculty of Medicine, Albert Szent\u2010Gy\u00f6rgyi Clinical Center University of Szeged  Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lajos","family":"Kem\u00e9ny","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology, Faculty of Medicine, Albert Szent\u2010Gy\u00f6rgyi Clinical Center University of Szeged  Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gy\u0151z\u0151","family":"Szolnoky","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology, Faculty of Medicine, Albert Szent\u2010Gy\u00f6rgyi Clinical Center University of Szeged  Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2014.08.011"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000006280"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1758-8111.2012.00045.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"crossref","unstructured":"BusoG DepaironM TomsonD et al.Lipedema: a call to action! 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