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We describe a rare case of a painless type A aortic dissection that occurred in an 85\u2010year\u2010old male, with moderate calcified aortic stenosis and a moderately dilated ascending aorta in 6\u2010month clinical and echocardiographic follow\u2010up. A chronic calculous cholecystitis with neutrophilic leukocytosis and severely increased C reactive protein was diagnosed in the last 3\u00a0months. In this patient, a chronic systemic inflammatory state might have contributed to generate the intimal entry tear in the aortic root. In particular, a neutrophil mobilization might have played a causative role in aortic rupture.<\/jats:p>","DOI":"10.1002\/jcu.22974","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T07:36:54Z","timestamp":1610696214000},"page":"682-685","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["An unusual case of painless type A aortic dissection"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7641-8831","authenticated-orcid":false,"given":"Andrea","family":"Sonaglioni","sequence":"first","affiliation":[{"name":"Department of Cardiology Ospedale San Giuseppe MultiMedica  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Lombardo","sequence":"additional","affiliation":[{"name":"Department of Cardiology Ospedale San Giuseppe MultiMedica  Milan 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