{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T13:47:12Z","timestamp":1793195232403,"version":"4.5.0"},"reference-count":47,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T00:00:00Z","timestamp":1622073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the clinical effectiveness of minimally invasive ultrasound (US)\u2010guided vs open release for carpal tunnel syndrome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In an open randomized controlled trial, 47 employed patients were allocated to US\u2010guided carpal tunnel release (USCTR) and 42 to an open carpal tunnel release (OCTR) procedure. The main outcome was symptom severity measured by the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ\u2010S). Secondary outcomes were hand functionality (BCTQ\u2010F), nerve conduction, two\u2010point discrimination, handgrip and pinch strength, pain (visual analog scale), work leave and complications. For BCTQ\u2010S and BCTQ\u2010F, minimal clinically important differences (MCID) were also considered. Follow\u2010up duration was 12\u2009months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mixed model analyses detected no significant differences between the two treatment arms in BCTQ\u2010S (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.098) while BCTQ\u2010F scores were significantly better in the USCTR group (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.007). This benefit was, however, not supported by the MCID data. Remaining variables were similar in the two groups except pain which was lower in USCTR at 3\u00a0months follow\u2010up. All variables but two\u2010point discrimination showed significant improvement after 3\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings reveal similar symptom relief benefits following OCTR or USCTR in these patients. The patients in our USCTR group, however, reported better hand functional status and less pain.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.23019","type":"journal-article","created":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T04:03:32Z","timestamp":1622174612000},"page":"693-703","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["<scp>Minimally invasive ultrasound\u2010guided<\/scp> vs <scp>open release for carpal tunnel syndrome in working population<\/scp>: A <scp>randomized controlled trial<\/scp>"],"prefix":"10.1002","volume":"49","author":[{"given":"Javier","family":"de la Fuente","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery Cl\u00ednica Pakea\u2010Mutualia  San Sebasti\u00e1n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3466-6516","authenticated-orcid":false,"given":"Jose 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