{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:17:37Z","timestamp":1790007457045,"version":"4.0.1"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T00:00:00Z","timestamp":1641340800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>We aimed to evaluate the clinical efficacy and safety of ultrasonographically (US)\u2010guided percutaneous microwave ablation (MWA) in the treatment of primary hyperparathyroidism (PHPT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 35 patients who received MWA treatment in our hospital between August, 2019 and January, 2021 were retrospectively analyzed. Serum parathyroid hormone (PTH), calcium, phosphorus levels, and improvement in clinical symptoms were recorded before and after MWA. All patients were followed up for 6\u2009months. Paired\u2010sample <jats:italic>t<\/jats:italic>\u2010tests and paired sample Wilcoxon signed\u2010rank tests were used to indicate PTH, calcium, and P levels before and after ablation. Postoperative complications were statistically analyzed to evaluate the therapeutic effect of MWA on PHPT patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 38 parathyroid nodules in 35 PHPT patients were completely ablated at one time. These results indicated that MWA could effectively destroy parathyroid tissue and decrease the concentrations of PTH, calcium, and phosphorus compared with those before MWA, and the effect was sustained. Moreover, MWA improved clinical symptoms, and improved quality of life of patients. None of patients developed tracheal and esophageal injuries, peripheral hematoma, infection, or other serious complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>US\u2010guided MWA has shown to be an effective and safe approach to treat PHPT patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.23134","type":"journal-article","created":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T08:45:16Z","timestamp":1641372316000},"page":"227-235","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Evaluation of efficacy of ultrasound\u2010guided microwave ablation in primary hyperparathyroidism"],"prefix":"10.1002","volume":"50","author":[{"given":"Mingzhu","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Abdominal Ultrasound The Affiliated Hospital of Qingdao University  Qingdao Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxiu","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Abdominal Ultrasound The Affiliated Hospital of Qingdao University  Qingdao Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Abdominal Ultrasound The Affiliated Hospital of Qingdao University  Qingdao Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoyan","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Abdominal Ultrasound The Affiliated Hospital of Qingdao University  Qingdao Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinya","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Abdominal Ultrasound The Affiliated Hospital of Qingdao University  Qingdao Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbin","family":"Jiang","sequence":"additional","affiliation":[{"name":"Health Management Center The Affiliated Hospital of Qingdao University  Qingdao Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9655-8866","authenticated-orcid":false,"given":"Cheng","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Abdominal Ultrasound The Affiliated Hospital of Qingdao University  Qingdao Shandong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,1,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.4158\/EP.11.1.49"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3724\/SP.J.1008.2013.00371"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2016160768"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60507-9"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2019.1707097"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-4022"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3724\/SP.J.1008.2013.00362"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-1413"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MED.0000000000000198"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2009.142"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2019.1627429"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.37015\/AUDT.2019.190805"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2020.1750712"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2021.1889601"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfv334"},{"key":"e_1_2_10_17_1","first-page":"928","article-title":"Ultrasound\u2010guided percutaneous microwave ablation in the treatment of hyperparathyroidism secondary to chronic renal failure","volume":"48","author":"Pan CQ","year":"2020","journal-title":"Chin J Clin"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2016151875"},{"key":"e_1_2_10_19_1","first-page":"835","article-title":"Comparison of ultrasound\u2010guided percutaneous microwave ablation and parathyroidectomy for primary hyperparathyroidism","volume":"36","author":"Liu F","year":"2019","journal-title":"Int J Hyperthermia"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.3372"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2019.1684576"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-42618-7_15"},{"key":"e_1_2_10_23_1","first-page":"547S","article-title":"Contrast\u2010enhanced ultrasound","volume":"80","author":"Furlow B","year":"2009","journal-title":"Radiol Technol"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mric.2017.06.004"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129689-200604000-00015"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-020-02511-1"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.20311"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.3109\/02656736.2015.1101788"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1053\/jarr.2002.34840"},{"key":"e_1_2_10_30_1","first-page":"537","article-title":"A retrospective case\u2010controlled study of video\u2010assisted versus open minimally invasive parathyroidectomy","volume":"9","author":"Barczy\u0144ski M","year":"2014","journal-title":"Wideochir Inne Tech Maloinwazyjne"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-019-06078-y"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.52.8454"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.11.8442"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2018.1528392"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.14949"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2019.0593"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/02656736.2020.1785557"},{"key":"e_1_2_10_38_1","first-page":"421","article-title":"Advances in the treatment of secondary hyperparathyroidism with ultrasound\u2010guided percutaneous thermal ablation(in Chinese)","volume":"15","author":"Luo L","year":"2016","journal-title":"Chinese Journal of Blood Purification"}],"container-title":["Journal of Clinical Ultrasound"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.23134","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jcu.23134","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jcu.23134","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T03:54:03Z","timestamp":1718942043000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jcu.23134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,5]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10.1002\/jcu.23134"],"URL":"https:\/\/doi.org\/10.1002\/jcu.23134","archive":["Portico"],"relation":{},"ISSN":["0091-2751","1097-0096"],"issn-type":[{"value":"0091-2751","type":"print"},{"value":"1097-0096","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,5]]},"assertion":[{"value":"2021-09-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}