{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T14:51:00Z","timestamp":1782831060780,"version":"3.54.5"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T00:00:00Z","timestamp":1646352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the prevalence of vesicoureteral reflux (VUR), febrile urinary tract infection (fUTI), and chronic kidney disease (CKD) among patients with multicystic dysplastic kidney (MCDK) diagnosed by renal scintigraphy (RS) versus follow\u2010up renal ultrasound (RUS) alone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective review of patients seen at a tertiary care center from 2010 to 2020 with MCDK diagnosed by RS or follow\u2010up RUS. Differences in the prevalence of VUR, fUTI, and CKD by cohort were assessed using logistic regression analysis, Pearson <jats:italic>X<\/jats:italic><jats:sup>2<\/jats:sup>, and Fisher's Exact tests. Temporal trends in diagnostic methods used (RUS versus RUS\u2009+\u2009RS) were evaluated using the Cochran\u2010Armitage trend test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One\u2010hundred seventy\u2010two patients were included: 50% (<jats:italic>n<\/jats:italic>\u00a0=\u00a086) underwent RUS\u2009+\u2009RS and 50% (<jats:italic>n<\/jats:italic>\u00a0=\u00a086) underwent RUS alone to diagnose MCDK. Prevalence of VUR, fUTI, and CKD did not significantly vary between groups. Among patients who had a VCUG, 4.4% had contralateral VUR (1.7% RUS\u2009+\u2009RS group; 7.4% RUS group; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.19) and 14.5% had at least one fUTI (16.3% RUS\u2009+\u2009RS group; 12.8% RUS group; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.52). Females were significantly more likely to have at least one fUTI (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.04). Four patients (2.3%) developed CKD, all in the RUS\u2009+\u2009RS cohort (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.12). Diagnosis of MCDK by RUS versus RUS\u2009+\u2009RS did not significantly vary over time (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.17).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with unilateral MCDK confirmed by RS versus RUS alone do not significantly vary in the prevalence of VUR, fUTI, or CKD. Renal scintigraphy studies may not be necessary in unilateral MCDK diagnosis but continue to be used.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.23172","type":"journal-article","created":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T05:00:08Z","timestamp":1646456408000},"page":"854-861","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Utility of renal scintigraphy in diagnosis of multicystic dysplastic kidney"],"prefix":"10.1002","volume":"50","author":[{"given":"Arthi","family":"Hannallah","sequence":"first","affiliation":[{"name":"Division of Urology Children's Hospital Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4929-1964","authenticated-orcid":false,"given":"Zo\u00eb G.","family":"Baker","sequence":"additional","affiliation":[{"name":"Division of Urology Children's Hospital Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger E.","family":"De Filippo","sequence":"additional","affiliation":[{"name":"Division of Urology Children's Hospital Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. 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