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This goal can be improved by the routine and focused sonographic assessment of specific anatomic planes and the identification of distinctive landmarks that can help disclosing a particular, non\u2010evident condition. In this article we present the basis for a basic, early examination of the fetal brain during screening using a four\u2010step technique, which can be readily incorporated during the first\u2010trimester scan. The technique includes the focused visualization of the cranial contour, choroid plexuses of the lateral ventricles and midline, aqueduct of Sylvius, brainstem, fourth ventricle, and the choroid plexus of the fourth ventricle. The rationale for this approach is presented and discussed.<\/jats:p>","DOI":"10.1002\/jcu.23337","type":"journal-article","created":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T06:19:30Z","timestamp":1676355570000},"page":"300-310","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Basic sonographic examination of the fetal brain at 11\u201313\u2009weeks' gestation: Rationale for a simple and reliable four\u2010step technique"],"prefix":"10.1002","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3856-574X","authenticated-orcid":false,"given":"Waldo","family":"Sepulveda","sequence":"first","affiliation":[{"name":"FETALMED\u2013Maternal\u2010Fetal Diagnostic Center Fetal Imaging Unit  Santiago 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