{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T15:20:01Z","timestamp":1747149601158,"version":"3.40.5"},"reference-count":37,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T00:00:00Z","timestamp":1684281600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The purpose of this study was to assess the skin involvement in systemic scleroderma patients (SSc) with 2D\u2010Shear Wave Elastography (2D\u2010SWE) and to review the corelation between skin elasticity and pulmonary involvement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty SSc patients and 30 controls were examined using 2D\u2010SWE. The demographics matched both groups. B\u2010mode ultrasound (US) and 2D\u2010SWE assessed skin thickness and elastography from the ventral side of the right forearm in each subjective. ROC analysis determined optimal group separation cut\u2010off values. A rheumatologist applied mRSS for SSc patients. US, mRSS, and pulmonary involvement correlations were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>US parameter values (skin thickness, median kPa, median m\/s) were higher in the SSc patient group (1.78\u2009\u00b1\u20090.36\u2009mm, 22.15\u2009\u00b1\u200916.26, 2.60\u2009\u00b1\u20090.82, respectively) compared to the control group (1.55\u2009\u00b1\u20090.2\u2009mm, 7.45\u2009\u00b1\u20091.84, 1.56\u2009\u00b1\u20090.2, respectively, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). When the optimal cut\u2010off SWE values for separating groups was determined as 10.5\u2009kPa and 1.87\u2009m\/s, the sensitivity was 93% and the specificity was 97%. Pearson's correlation analysis showed a strong positive correlation between mRSS and median SWE values (kPa, <jats:italic>r<\/jats:italic>\u2009=\u20090.626, <jats:italic>p<\/jats:italic>\u2009=\u20090.001; m\/s, <jats:italic>r<\/jats:italic>\u2009=\u20090.638, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). There was no correlation between pulmonary involvement of SSc patients with mRSS and US parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>2D\u2010SWE is a promising non\u2010invasive method to evaluate skin involvement in SSc patient group. For pulmonary involvement we need more data with bigger patient groups.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.23488","type":"journal-article","created":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T06:52:14Z","timestamp":1684392734000},"page":"1205-1211","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Assessment of the skin with 2<scp>D<\/scp>\u2010shear wave elastography in the systemic scleroderma and its correlation with pulmonary involvement"],"prefix":"10.1002","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1097-1172","authenticated-orcid":false,"given":"Ahmet","family":"Tanyeri","sequence":"first","affiliation":[{"name":"Department of Radiology, Faculty of Medicine Ayd\u0131n Adnan Menderes University  Ayd\u0131n Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2371-3540","authenticated-orcid":false,"given":"Mehmet 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