{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T17:51:51Z","timestamp":1789667511697,"version":"4.0.1"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T00:00:00Z","timestamp":1686787200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>We aimed to compare the diagnostic performance of magnetic resonance imaging (MRI) and transvaginal ultrasound (TVS) for detecting myometrial invasion (MI) in patients with low\u2010grade endometrioid endometrial carcinoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A comprehensive search of MEDLINE (Pubmed), Web of Science, Embase and Scopus (from January 1990 to December 2022) was performed for articles comparing TVS and MRI in the evaluation of myometrial infiltration in low\u2010grade (grade 1 or 2) endometrioid endometrial carcinoma in the same group of patients. We used QUADAS\u20102 tool for assessing the risk of bias of studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found 104 citations in our extensive research. Four articles were ultimately included in the meta\u2010analysis, after excluding 100 reports. All articles were considered low risk of bias in most of the domains assessed in QUADAS\u20102. We observed that pooled sensitivity and specificity for detecting deep MI were 65% (95% confidence interval [CI]\u2009=\u200954%\u201375%) and 85% (95% CI\u2009=\u200979%\u201389%) for MRI, and 71% (95% CI\u2009=\u200963%\u201378%) and 76% (95% CI\u2009=\u200967%\u201383%) for TVS, respectively. No statistical differences were found between both imaging techniques (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). We observed low heterogeneity for sensitivity and high for specificity regarding TVS; and moderate for both sensitivity and specificity in case of MRI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The diagnostic performance of TVS and MRI for the evaluation of deep MI in women with low\u2010grade endometrioid endometrial cancer is similar. However, further research is needed as the number of studies is scanty.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.23508","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T13:46:40Z","timestamp":1686836800000},"page":"1188-1197","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Transvaginal ultrasound versus magnetic resonance imaging for preoperative assessment of myometrial infiltration in patients with low\u2010grade endometrioid endometrial cancer: A systematic review and head\u2010to\u2010head meta\u2010analysis"],"prefix":"10.1002","volume":"51","author":[{"given":"Sara","family":"Tameish","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospital Sant Joan  Reus Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Florez","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospital Virgen de Valme  Seville Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Ram\u00f3n P\u00e9rez","family":"Vidal","sequence":"additional","affiliation":[{"name":"Department Obstetrics and Gynecology University Hospital Virgen de la Arrixaca  Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University Hospital Castell\u00f3  Castell\u00f3 de la Plana Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"Vara","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Clinica Universidad de Navarra  Pamplona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9700-0853","authenticated-orcid":false,"given":"Juan Luis","family":"Alc\u00e1zar","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Clinica Universidad de Navarra  Pamplona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,15]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"Classification of Tumours","author":"WHO Classification of Tumours Editorial Board","year":"2020"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)00323-3"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2021.01.036"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(89)90027-9"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc-2020-002230"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000000618"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5295"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2011.11.016"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/IGC.0b013e3181ad3eb6"},{"key":"e_1_2_11_11_1","unstructured":"SEGO.Oncogu\u00eda SEGO:C\u00e1ncer de endometrio; 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