{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T12:38:10Z","timestamp":1775133490155,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T00:00:00Z","timestamp":1712880000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Clinical Ultrasound"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>We aimed to develop and validate a new ultrasonography (US) index for the diagnosis of primary medial\u2010type knee osteoarthritis (OA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In total, 156 patients (203 limbs) underwent standing knee radiography and the US for suspected knee OA. Total osteophyte height (TOH) and distance between bones (DBB) aided diagnosis. Logistic regression identified optimal cutoff values. Thresholds from logistic regression informed recipient operating characteristic curve (ROC) analysis, balancing sensitivity and specificity. These thresholds were then applied in the differential thermal analysis (DTA) to construct a 2\u2009\u00d7\u20092 table.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The TOH\u2010DBB index showed that a DBB of 5.6\u2009mm or less was required to diagnose primary medial\u2010type knee arthropathy. The results in the 2\u2009\u00d7\u20092 table were 41 true\u2010positive (TP), 10 false negative (FN), 22 true\u2010negative (TN), and 7 false positive (FP). A DBB of 5.6\u2009mm or less and TOH of 4.7\u2009mm or more were necessary to diagnose severe deformity. The results in the 2\u2009\u00d7\u20092 table were 10 TP, 4 FN, 23 TN, and 4 FP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The TOH\u2010DBB index was confirmed to capture changes in primary medial\u2010type knee OA across various stages.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jcu.23691","type":"journal-article","created":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T18:30:00Z","timestamp":1712946600000},"page":"687-699","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Diagnostic accuracy of a novel ultrasound imaging index for knee osteoarthritis: Evaluation of sensitivity, specificity, and predictive values"],"prefix":"10.1002","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7905-7453","authenticated-orcid":false,"given":"Takeharu","family":"Kiso","sequence":"first","affiliation":[{"name":"Department of Radiology Medical Corporation Seireikai Tachikawa 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